Investigation on the binding behavior of human α1-acid glycoprotein with Janus Kinase inhibitor baricitinib: Multi-spectroscopic and molecular simulation …

SL Jiang, ZY Hu, WJ Wang, L Hu, L Li, SB Kou… - International Journal of …, 2023 - Elsevier
Abstract Baricitinib is a Janus Kinase (JAK) inhibitor that is primarily used to treat moderately
to severely active rheumatoid arthritis in adults and has recently been reported for the …

Unravelling the thermodynamics and binding interactions of bovine serum albumin (BSA) with thiazole based carbohydrazide: Multi-spectroscopic, DFT and molecular …

P Rani, S Chahal, R Kataria, P Kumar, S Kumar… - Journal of Molecular …, 2022 - Elsevier
In the present manuscript, a novel 2-((4-chlorophenyl) amino)-N'-(4-(diethylamino)-2-
hydroxybenzylidene) thiazole-4-carbohydrazide (H1) has been synthesized and …

Comprehending the intermolecular interaction of JAK inhibitor fedratinib with bovine serum albumin (BSA)/human alpha-1-acid glycoprotein (HAG): Multispectral …

SL Jiang, WJ Wang, ZY Hu, RJ Zhang, JH Shi - Spectrochimica Acta Part A …, 2024 - Elsevier
The primary coverage of this paper is to investigate the molecular interaction of JAK2
inhibitor, fedratinib (FED) with BSA/HAG proteins through multispectral approaches and …

α-Amylase inhibition, anti-glycation property and characterization of the binding interaction of citric acid with α-amylase using multiple spectroscopic, kinetics and …

OJ Avwioroko, AA Anigboro, CA Otuechere… - Journal of Molecular …, 2022 - Elsevier
The quest to suppress complications associated with diabetes mellitus is ever increasing,
while food additives and preservatives are currently being considered to play additional …

Exploring the binding characteristics of bovine serum albumin with tyrosine kinase inhibitor entrectinib: Multi-spectral analysis and theoretical calculation

SL Jiang, L Hu, ZY Hu, WJ Wang, JH Shi - Spectrochimica Acta Part A …, 2023 - Elsevier
Entrectinib (ENB) is one of multi-target tyrosine kinase inhibitors, which is mainly used for
treating neurotrophic tyrosine receptor kinase gene fusion positive solid tumors. The binding …

Characterization of sulfasalazine-bovine serum albumin and human serum albumin interaction by spectroscopic and theoretical approach

N Rahman, N Khalil - Spectrochimica Acta Part A: Molecular and …, 2023 - Elsevier
The interaction of sulfasalazine (SZ) with the carrier proteins bovine serum albumin (BSA)
and human serum albumin (HSA) was explored by fluorescence, absorption and circular …

Insights into the interaction between the kusaginin and bovine serum albumin: Multi‐spectroscopic techniques and computational approaches

F Huang, C Chen - Journal of Molecular Recognition, 2023 - Wiley Online Library
Kusaginin, as a phenylethanoid glycoside, which has exhibited wide antioxidant and
antimicrobial properties. The molecular mechanism underlying the broad biological activities …

Molecular Recognition Study toward the Mitochondrial Electron Transport Chain Inhibitor Mubritinib and Human Serum Albumin

TM Menezes, G Seabra, JL Neves - Molecular Pharmaceutics, 2023 - ACS Publications
The ability to bind plasma proteins helps in comprehending relevant aspects related to the
pharmacological properties of many drugs. Despite the vital role of the drug mubritinib …

Quinoxaline-derived “turn-off” fluorescent sensor for the selective detection of Fe3+: Synthesis, spectroscopic analysis, BSA binding and computational studies

L Narayan, J Sindhu, P Kumar, A Kumar… - Journal of Molecular …, 2023 - Elsevier
A simple quinoxaline-based “turn-off” fluorescent sensor 12-{[1-(4-isopropylphenyl)-1H-1, 2,
3-triazol-5-yl] methyl} c-12H-benzo [5, 6][1, 4] thiazino [2, 3-b] quinoxaline (BTQT) was …

In vitro and in silico insights into the molecular interaction mechanism of acetylshikonin with bovine serum albumin

L Khalili, G Dehghan, AA Moosavi-Movahedi… - Journal of Molecular …, 2022 - Elsevier
Acetylshikonin (ASK), as a privileged naphthoquinone derivative with unique spectroscopic
properties, is considered an effective substance in biomedical areas. This manuscript was …