Chronic myeloid leukemia (CML) is the prototype cytogenetic malignancy. Even before the
development of basic G-and R-banding techniques, CML was found to be associated with a …

Chronic myeloid leukemia (CML) is characterized by the presence of the BCR-ABL1 fusion
gene. In more than 95% of CML patients, the typical BCR-ABL1 transcript subtypes are …

Objectives Achieving a major molecular response (MMR) is the goal of imatinib therapy for
chronic myeloid leukemia. However, the association between gender, BCR‐ABL transcript …

Purpose: The aim of this study was to search the BCR/ABL 1 fusion gene in 45 chronic
myeloid leukemia (CML) Syrian patients using nested reverse transcription polymerase …

Abstract Background Chronic Myeloid Leukemia (CML) is characterized by the
overproduction of BCR-ABL, a tyrosine kinase with constitutive activity, in which the majority …

Although the majority of patients with chronic myeloid leukemia do well with treatment with
tyrosine kinase inhibitors (TKIs), some patients still have inferior outcomes. There are many …

Background Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm
characterized by the presence of BCR‐ABL fusion gene (GenBank accession NC_000022 …

Objectives: There are very few published chronic myeloid leukaemia (CML) epidemiology
studies in South-East Asia and no representative from Malaysia. Methods: This is a cross …

Background: A specific chromosomal abnormality, the Philadelphia chromosome (BCR-ABL
fusion), is present in all patients with chronic myeloid leukemia (CML). The b2a2 and b3a2 …

Introduction and objective: In this study, we evaluated the influence of the transcript type on
hematological and clinical parameters, as well as the event-free survival of 50 patients in the …