Pharmacogenomics: driving personalized medicine

W Sadee, D Wang, K Hartmann, AE Toland - Pharmacological reviews, 2023 - ASPET
Personalized medicine tailors therapies, disease prevention, and health maintenance to the
individual, with pharmacogenomics serving as a key tool to improve outcomes and prevent …

[HTML][HTML] Personalized medicine and the power of electronic health records

NS Abul-Husn, EE Kenny - Cell, 2019 - cell.com
Personalized medicine has largely been enabled by the integration of genomic and other
data with electronic health records (EHRs) in the United States and elsewhere. Increased …

PharmVar GeneFocus: CYP2D6

C Nofziger, AJ Turner, K Sangkuhl… - Clinical …, 2020 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly
polymorphic human CYP2D6 gene locus. CYP2D6 genetic variation impacts the metabolism …

PharmVar GeneFocus: CYP2C19

MR Botton, M Whirl‐Carrillo… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation …

[HTML][HTML] Pharmacogenomics in practice: A review and implementation guide

D Kabbani, R Akika, A Wahid, AK Daly… - Frontiers in …, 2023 - frontiersin.org
Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study
of interindividual variations in DNA sequence related to drug response, into routine clinical …

ASHP statement on the pharmacist's role in clinical pharmacogenomics

CE Haidar, N Petry, C Oxencis… - American Journal of …, 2022 - academic.oup.com
Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …

PharmVar GeneFocus: CYP2C9

K Sangkuhl, K Claudio‐Campos… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C9 gene. Genetic variation within the …

PharmVar GeneFocus: CYP3A5

C Rodriguez‐Antona, JL Savieo… - Clinical …, 2022 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogs star (*) allele nomenclature
for the polymorphic human CYP3A5 gene. Genetic variation within the CYP3A5 gene locus …

[HTML][HTML] Advancing pharmacogenomics from single-gene to preemptive testing

CE Haidar, KR Crews, JM Hoffman… - Annual review of …, 2022 - annualreviews.org
Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Pharmacogenomic clinical decision support: a review, how‐to guide, and future vision

DT Wake, DM Smith, S Kazi… - Clinical Pharmacology …, 2022 - Wiley Online Library
Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …