The term ''adrenergic''originates from ''adrenaline''and describes hormones or drugs whose
effects are similar to those of epinephrine. Adrenergic stress is mediated by stimulation of …

Background: Combination of vitamin C, hydrocortisone and thiamine have recently been
used in sepsis but data of efficacy are conflicting and no data are available from developing …

Rationale: Diagnosis of adrenal insufficiency in critically ill patients has relied on random or
cosyntropin-stimulated cortisol levels, and has not been corroborated by a more accurate …

Despite more than 5 decades of study and debate, the role of corticosteroid treatment in
patients with severe sepsis and septic shock remains controversial. Data support a …

Objective To determine the incidence and duration of adrenal inhibition induced by a single
dose of etomidate in critically ill patients. Design Prospective, observational cohort study …

A recent study suggested mortality benefits using vitamin C, hydrocortisone, and thiamine
combination therapy (triple therapy) in addition to standard care in patients with severe …

BACKGROUND: Because etomidate impairs adrenal function and blunts the cortisol release
associated with surgical stimulus, we hypothesized that patients induced with etomidate …

Ecological immunology provides a broad theoretical perspective on phenotypic plasticity in
immunity, that is, changes related to the value of immunity across different situations …

Objective: To evaluate the effects of hydrocortisone on microcirculatory blood flow
alterations in patients with septic shock. Design: Prospective, open-label study. Setting: A 31 …

One of the more controversial areas in critical care in recent decades relates to the issue of
adrenal insufficiency and its treatment in critically ill patients. There is no consensus on …