The normative modeling framework for computational psychiatry
Normative modeling is an emerging and innovative framework for mapping individual
differences at the level of a single subject or observation in relation to a reference model. It …
differences at the level of a single subject or observation in relation to a reference model. It …
Precision behavioral phenotyping as a strategy for uncovering the biological correlates of psychopathology
Our capacity to measure diverse aspects of human biology has developed rapidly in the past
decades, but the rate at which these techniques have generated insights into the biological …
decades, but the rate at which these techniques have generated insights into the biological …
Evidence for embracing normative modeling
In this work, we expand the normative model repository introduced in Rutherford et al.,
2022a to include normative models charting lifespan trajectories of structural surface area …
2022a to include normative models charting lifespan trajectories of structural surface area …
Charting brain growth and aging at high spatial precision
Defining reference models for population variation, and the ability to study individual
deviations is essential for understanding inter-individual variability and its relation to the …
deviations is essential for understanding inter-individual variability and its relation to the …
[HTML][HTML] Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation
R Ge, Y Yu, YX Qi, Y Fan, S Chen, C Gao… - The Lancet Digital …, 2024 - thelancet.com
The value of normative models in research and clinical practice relies on their robustness
and a systematic comparison of different modelling algorithms and parameters; however …
and a systematic comparison of different modelling algorithms and parameters; however …
Closing the life-cycle of normative modeling using federated hierarchical Bayesian regression
Clinical neuroimaging data availability has grown substantially in the last decade, providing
the potential for studying heterogeneity in clinical cohorts on a previously unprecedented …
the potential for studying heterogeneity in clinical cohorts on a previously unprecedented …
[HTML][HTML] Warped Bayesian linear regression for normative modelling of big data
Normative modelling is becoming more popular in neuroimaging due to its ability to make
predictions of deviation from a normal trajectory at the level of individual participants. It …
predictions of deviation from a normal trajectory at the level of individual participants. It …
Interindividual differences in cortical thickness and their genomic underpinnings in autism spectrum disorder
C Ecker, CM Pretzsch, A Bletsch… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Autism spectrum disorder (ASD) is accompanied by highly individualized
neuroanatomical deviations that potentially map onto distinct genotypes and clinical …
neuroanatomical deviations that potentially map onto distinct genotypes and clinical …
[HTML][HTML] Chinese Color Nest Project: An accelerated longitudinal brain-mind cohort
S Liu, YS Wang, Q Zhang, Q Zhou, LZ Cao… - Developmental …, 2021 - Elsevier
Abstract The ongoing Chinese Color Nest Project (CCNP) was established to create
normative charts for brain structure and function across the human lifespan, and link age …
normative charts for brain structure and function across the human lifespan, and link age …
Current approaches in computational psychiatry for the data-driven identification of brain-based subtypes
The ability of our current psychiatric nosology to accurately delineate clinical populations
and inform effective treatment plans has reached a critical point with only moderately …
and inform effective treatment plans has reached a critical point with only moderately …