Progress in understanding the IL-6/STAT3 pathway in colorectal cancer

Y Lin, Z He, J Ye, Z Liu, X She, X Gao… - OncoTargets and …, 2020 - Taylor & Francis
As a pleiotropic cytokine, interleukin-6 (IL-6) not only regulates the cellular immune
response, but it also promotes tumor development by activating multiple carcinogenic …

Near-infrared II emissive metal clusters: From atom physics to biomedicine

H Ma, J Wang, XD Zhang - Coordination Chemistry Reviews, 2021 - Elsevier
Abstract Near-infrared II (NIR-II) imaging at 1100–1700 nm supports deep tissue
penetration, low auto-fluorescence interruption, and high imaging resolution due to …

T-cell-based immunotherapy in colorectal cancer

M Feng, Z Zhao, M Yang, J Ji, D Zhu - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is the leading cause of cancer death worldwide. CRC therapeutic
strategies include surgical resection, chemotherapy, radiotherapy, and other approaches …

A methylation-and immune-related lncRNA signature to predict ovarian cancer outcome and uncover mechanisms of chemoresistance

L Chen, W Gao, L Lin, C Sha, T Li, Q Chen… - Journal of Ovarian …, 2023 - Springer
Tumor-associated lncRNAs regulated by epigenetic modification switches mediate immune
escape and chemoresistance in ovarian cancer (OC). However, the underlying mechanisms …

Targeted immunotherapies in gastrointestinal cancer: from molecular mechanisms to implications

DK Wang, Q Zuo, QY He, B Li - Frontiers in immunology, 2021 - frontiersin.org
Gastrointestinal cancer is a leading cause of cancer-related mortality and remains a major
challenge for cancer treatment. Despite the combined administration of modern surgical …

Cell therapy for colorectal cancer: the promise of chimeric antigen receptor (CAR)-T cells

C Aparicio, M Belver, L Enríquez, F Espeso… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a global public health problem as it is the third most prevalent
and the second most lethal cancer worldwide. Major efforts are underway to understand its …

MiR-21 modulates the polarization of macrophages and increases the effects of M2 macrophages on promoting the chemoresistance of ovarian cancer

Y An, Q Yang - Life sciences, 2020 - Elsevier
Aims Chemoresistance is a major underlying cause of relapse or death in ovarian cancer
patients. Emerging evidence has shown that macrophages could play an essential role in …

Deciphering the mechanism of Peptostreptococcus anaerobius-induced chemoresistance in colorectal cancer: the important roles of MDSC recruitment and EMT …

J Gu, X Lv, W Li, G Li, X He, Y Zhang, L Shi… - Frontiers in …, 2023 - frontiersin.org
Peptostreptococcus anaerobius (P. anaerobius, PA) in intestinal flora of patients with
colorectal cancer (CRC) are associated with poor prognosis. Studies have shown that P …

[HTML][HTML] Global whole family based-Helicobacter pylori eradication strategy to prevent its related diseases and gastric cancer

SZ Ding - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infects approximately 50% of the world population. The
multiple gastrointestinal and extra-gastrointestinal diseases caused by H. pylori infection …

Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite …

T Wu, X Zhang, X Liu, X Cai, T Shen, D Pan, R Liang… - BMC medicine, 2023 - Springer
Background The objective response rate of microsatellite instability-high (MSI-H) metastatic
colorectal cancer (mCRC) patients with first-line anti-programmed cell death protein-1 (PD …