[HTML][HTML] Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion

N Rodman, J Martinez, S Fung, J Nakanouchi… - Frontiers in …, 2019 - frontiersin.org
Acinetobacter baumannii (Ab) is one of the most treacherous pathogens among those
causing hospital-acquired pneumonia (HAP). A. baumannii possesses an adaptable …

[HTML][HTML] Clinical features and outcomes of monobacterial and polybacterial episodes of ventilator-associated pneumonia due to multidrug-resistant Acinetobacter …

D Adukauskiene, A Ciginskiene, A Adukauskaite… - Antibiotics, 2022 - mdpi.com
Multidrug-resistant A. baumannii (MDRAB) VAP has high morbidity and mortality, and the
rates are constantly increasing globally. Mono-and polybacterial MDRAB VAP might differ …

Investigational drugs for the treatment of infections caused by multidrug-resistant Gram-negative bacteria

LM Avery, DP Nicolau - Expert opinion on investigational drugs, 2018 - Taylor & Francis
Introduction: Infections caused by multidrug-resistant Gram-negative bacteria (MDR-GNB)
are associated with significant mortality and costs. New drugs in development to combat …

Outer Membrane Vesicle‐Coated Nanoparticle Vaccine Protects against Acinetobacter baumannii Pneumonia and Sepsis

E Bjanes, J Zhou, T Qayum, N Krishnan… - Advanced …, 2023 - Wiley Online Library
The highly multidrug‐resistant (MDR) Gram‐negative bacterial pathogen Acinetobacter
baumannii is a top global health priority where an effective vaccine can protect susceptible …

Replication initiator proteins of Acinetobacter baumannii plasmids: an update note

S Castro-Jaimes, G Guerrero, E Bello-López… - Plasmid, 2022 - Elsevier
The bioinformatic analysis that we made of 492 Acinetobacter baumannii plasmid
sequences identified 418 genes encoding Replication Initiator (Rep) proteins that fell into at …

The effectiveness of oral care guideline implementation on oral health status in critically ill patients

IH Khasanah, W Sae-Sia… - SAGE Open Nursing, 2019 - journals.sagepub.com
Intubated patients need specific oral care due to the use of endotracheal tubes. An oral
nursing care guideline needs to be implemented to guide nurses in oral care in intubated …

Carbapenem-Resistant Acinetobacter spp Infection in Critically Ill Patients With Limited Treatment Options: A Descriptive Study of Cefiderocol Therapy During the …

M Giannella, S Verardi, A Karas… - Open Forum …, 2023 - academic.oup.com
Abstract Background Carbapenem-resistant Acinetobacter baumannii infections are difficult
to treat and are a significant public health threat due to intrinsic/acquired resistance and …

An outer membrane protein YiaD contributes to adaptive resistance of meropenem in Acinetobacter baumannii

L Han, Y Gao, Y Liu, S Yao, S Zhong… - Microbiology …, 2022 - Am Soc Microbiol
Acinetobacter baumannii is an important nosocomial pathogen that can develop various
resistance mechanisms to many antibiotics. However, little is known about how it evolves …

[HTML][HTML] Pathogenesis-targeted preventive strategies for multidrug resistant ventilator-associated pneumonia: a narrative review

A Cotoia, S Spadaro, G Gambetti, D Koulenti… - Microorganisms, 2020 - mdpi.com
Ventilator-associated pneumonia (VAP) is the most common hospital-acquired infection in
the intensive care unit (ICU), accounting for relevant morbidity and mortality among critically …

[HTML][HTML] Iron-Rich Conditions Induce OmpA and Virulence Changes of Acinetobacter baumannii

H Liu, CY Cao, F Qiu, HN Huang, H Xie… - Frontiers in …, 2021 - frontiersin.org
Background: Iron ions affect the expression of outer membrane protein A (OmpA), a major
pathogenic protein in Acinetobacter baumannii. Objective: To analyze the effect of iron ions …