[HTML][HTML] Recent developments in essentiality of trivalent chromium and toxicity of hexavalent chromium: Implications on human health and remediation strategies

A Monga, AB Fulke, D Dasgupta - Journal of Hazardous Materials …, 2022 - Elsevier
Among the many heavy metals, chromium (Cr) is one of the fascinating ones. In its two most
prevalent oxidation forms, trivalent (Cr 3+) and hexavalent (Cr 6+), Cr has completely …

Molecular and epigenetic mechanisms of Cr (VI)-induced carcinogenesis

QY Chen, A Murphy, H Sun, M Costa - Toxicology and applied …, 2019 - Elsevier
Chromium (Cr) is a naturally occurring metallic element found in the Earth's crust. While
trivalent chromium ([Cr (III)] is considered non-carcinogenic, hexavalent chromium [Cr (VI)] …

The double face of metals: The intriguing case of chromium

G Genchi, G Lauria, A Catalano, A Carocci… - Applied Sciences, 2021 - mdpi.com
Chromium (Cr) is a common element in the Earth's crust. It may exist in different oxidation
states, Cr (0), Cr (III) and Cr (VI), with Cr (III) and Cr (VI) being relatively stable and largely …

[HTML][HTML] Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N6 …

Y Lv, T Li, M Yang, L Su, Z Zhu, S Zhao… - Frontiers in Cell and …, 2021 - frontiersin.org
Spermatogonial stem cells (SSCs) are the basis of spermatogenesis, and any damage to
SSCs may result in spermatogenic disorder and male infertility. Chromium (Cr)(VI) is a …

Epigenetic regulation in chromium-, nickel-and cadmium-induced carcinogenesis

L Zhao, R Islam, Y Wang, X Zhang, LZ Liu - Cancers, 2022 - mdpi.com
Simple Summary Environmental and occupational exposure to heavy metals are risk factors
for cancers. However, the molecular mechanisms of how heavy metals induce …

Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis

JE Rager, M Suh, GA Chappell, CM Thompson… - Toxicology letters, 2019 - Elsevier
Inhalation exposure to hexavalent chromium [Cr (VI)] is associated with increased risk of
lung cancer with a mode of action (MOA) postulated to involve non-mutagenic key events …

[HTML][HTML] Biomarkers of effect as determined in human biomonitoring studies on hexavalent chromium and cadmium in the period 2008–2020

C Ventura, BC Gomes, A Oberemm, H Louro… - Environmental …, 2021 - Elsevier
A number of human biomonitoring (HBM) studies have presented data on exposure to
hexavalent chromium [Cr (VI)] and cadmium (Cd), but comparatively few include results on …

Epigenetic alterations of CXCL5 in Cr (VI)-induced carcinogenesis

X Ge, J He, L Wang, L Zhao, Y Wang, G Wu… - Science of the Total …, 2022 - Elsevier
Chronic exposure to hexavalent chromium compounds [Cr (VI)] is associated with an
increased risk of cancers, but the molecular mechanisms remain to be elucidated. In this …

Identification of epigenetic mechanisms in paddy crop associated with lowering environmentally related cadmium risks to food safety

SJ Feng, XS Liu, LY Ma, JK Rono, ZM Yang - Environmental pollution, 2020 - Elsevier
Cadmium (Cd) is a toxic metal that contributes to human diseases such as pediatric cancer
and cardiovascular dysfunction. Epigenetic modification caused by Cd exposure is the major …

Circulating differential miRNAs profiling and expression in hexavalent chromium exposed electroplating workers

J Jia, T Li, C Yao, J Chen, L Feng, Z Jiang, L Shi, J Liu… - Chemosphere, 2020 - Elsevier
Abstract Hexavalent chromium [Cr (Ⅵ)] has extensive applications in industries, and long-
term occupational exposure to Cr (Ⅵ) may lead to lung carcinoma and other cancers. While …