Endocrine disrupting chemicals and disease susceptibility

TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …

[HTML][HTML] Human infertility: are endocrine disruptors to blame?

A Marques-Pinto, D Carvalho - Endocrine connections, 2013 - ec.bioscientifica.com
Over recent decades, epidemiological studies have been reporting worrisome trends in the
incidence of human infertility rates. Extensive detection of industrial chemicals in human …

Diethylstilboestrol—a long-term legacy

RM Harris, RH Waring - Maturitas, 2012 - Elsevier
Diethylstilboestrol (DES) is an endocrine disrupter which causes cancer in rodents. It was
prescribed in large amounts to treat women with gynaecological problems; some of the …

Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A: The role of transmembrane G-protein estrogen receptor 1 and integrin αvβ3

Z Sheng, C Wang, F Ren, Y Liu, B Zhu - Journal of Environmental Sciences, 2019 - Elsevier
Bisphenol A (BPA) is one of the highest volume industrial products worldwide and has been
widely used to make various products as the intermediates of polycarbonate plastics and …

[HTML][HTML] Genetic syndromes and genes involved in the development of the female reproductive tract: a possible role for gene therapy

MT Connell, CM Owen, JH Segars - Journal of genetic syndromes …, 2013 - ncbi.nlm.nih.gov
Müllerian and vaginal anomalies are congenital malformations of the female reproductive
tract resulting from alterations in the normal developmental pathway of the uterus, cervix …

Neonatal exposure to a glyphosate-based herbicide alters the uterine differentiation of prepubertal ewe lambs

R Alarcón, OE Rivera, PI Ingaramo, MV Tschopp… - Environmental …, 2020 - Elsevier
The exposure to endocrine-disrupting compounds (EDCs), such as glyphosate-based
herbicides (GBHs), during early life might alter female fertility. The aim of the present study …

Uterine ERα epigenetic modifications are induced by the endocrine disruptor endosulfan in female rats with impaired fertility

MM Milesi, J Varayoud, JG Ramos, EH Luque - Molecular and cellular …, 2017 - Elsevier
High ERα activity may disrupt the window of uterine receptivity, causing defective
implantation. We investigated whether implantation failures prompted by endosulfan are …

Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats

MM Milesi, R Alarcón, JG Ramos… - Molecular and cellular …, 2015 - Elsevier
We investigated whether neonatal exposure to low doses of endosulfan affects fertility and
uterine functional differentiation at pre-implantation in rats. Newborn female rats received …

Evaluation of different wastewater treatment techniques in three WWTPs in Istanbul for the removal of selected EDCs in liquid phase

ZS Can, M Fırlak, A Kerç, S Evcimen - Environmental monitoring and …, 2014 - Springer
Endocrine-disrupting compounds (EDCs) are exogenous substances that cause adverse
health effects in an intact organism, or its progeny, subsequent to the changes in endocrine …

[HTML][HTML] Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Y Imamichi, T Sekiguchi, T Kitano, T Kajitani… - Scientific reports, 2017 - nature.com
Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the
reproductive system. In this study, we investigated the effects of DES administration on …