Pristine gelatin incorporation as a strategy to enhance the biofunctionality of poly (vinyl alcohol)-based hydrogels for tissue engineering applications

A Longoni, GS Major, S Jiang, BL Farrugia… - Biomaterials …, 2024 - pubs.rsc.org
Synthetic polymers, such as poly (vinyl alcohol)(PVA), are popular biomaterials for the
fabrication of hydrogels for tissue engineering and regenerative medicine (TERM) …

Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate …

IN Gavrilovskaya, EE Gorbunova, NA Mackow… - Journal of …, 2008 - Am Soc Microbiol
Hantaviruses infect human endothelial cells and cause two vascular permeability-based
diseases: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome …

Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance

J Gault, H Sarin, NA Awadallah, R Shenkar… - Neurosurgery, 2004 - journals.lww.com
Abstract CEREBROVASCULAR MALFORMATIONS AFFECT more than 3% of the
population, exposing them to a lifetime risk of hemorrhagic stroke, seizures, and focal …

Stable interaction between α5β1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1

I Cascone, L Napione, F Maniero, G Serini… - The Journal of cell …, 2005 - rupress.org
During angiogenic remodeling, Ang-1, the ligand of Tie2 tyrosine kinase, is involved in
vessel sprouting and stabilization through unclear effects on nascent capillaries and mural …

Neuropilins in the context of tumor vasculature

S Niland, JA Eble - International journal of molecular sciences, 2019 - mdpi.com
Neuropilin-1 and Neuropilin-2 form a small family of plasma membrane spanning receptors
originally identified by the binding of semaphorin and vascular endothelial growth factor …

Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice

M Chrzanowska-Wodnicka, AE Kraus… - Blood, The Journal …, 2008 - ashpublications.org
Angiogenesis is the main mechanism of vascular remodeling during late development and,
after birth, in wound healing. Perturbations of angiogenesis occur in cancer, diabetes …

Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with β1 integrin-and phosphatidylinositol 3-kinase-dependent PKCα …

K Podar, YT Tai, BK Lin, RP Narsimhan… - Journal of biological …, 2002 - ASBMB
In multiple myeloma (MM), migration is necessary for the homing of tumor cells to bone
marrow (BM), for expansion within the BM microenvironment, and for egress into the …

RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development

I Adini, I Rabinovitz, JF Sun… - Genes & …, 2003 - genesdev.cshlp.org
Blood vessel formation is a complex morphological process that is only beginning to be
understood at the molecular level. In this study, we demonstrate a novel and critical role for …

Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation

W Yan, R Shao - Journal of Biological Chemistry, 2006 - ASBMB
Tumor metastasis is a multistep pathological process involved in the final phase of tumor
development. During this process, epithelium-derived tumor cells undergo fibroblast-like …

Plasticity of tumor cell invasion: governance by growth factors and cytokines

J Odenthal, R Takes, P Friedl - Carcinogenesis, 2016 - academic.oup.com
Tumor cell migration, the basis for metastatic dissemination, is an adaptive process which
depends upon coordinated cell interaction with the environment, influencing cell–matrix and …