Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

During sleep, animals do not eat, reproduce or forage. Sleeping animals are vulnerable to
predation. Yet, the persistence of sleep despite evolutionary pressures, and the deleterious …

Do all animals sleep? Sleep has been observed in many vertebrates, and there is a growing
body of evidence for sleep-like states in arthropods and nematodes [1–5]. Here we show …

INTRODUCTION Global brain states such as sleep and wakefulness involve
reconfigurations of neural circuit activity across the entire nervous system. Yet it is not …

In recent years, genome-wide profiling approaches have begun to uncover the molecular
programs that drive developmental processes. In particular, technical advances that enable …

Animal behaviors are commonly organized into long-lasting states that coordinately impact
the generation of diverse motor outputs such as feeding, locomotion, and grooming …

Animals with complex nervous systems demand sleep for memory consolidation and
synaptic remodeling. Here, we show that, although the Caenorhabditis elegans nervous …

Glia are abundant components of animal nervous systems. Recognized 170 years ago,
concerted attempts to understand these cells began only recently. From these investigations …

The antiparasitic drug ivermectin plays an essential role in human and animal health
globally. However, ivermectin resistance is widespread in veterinary helminths and there are …

The selection and execution of context-appropriate behaviors is controlled by the integrated
action of neural circuits throughout the brain. However, how activity is coordinated across …