[HTML][HTML] Hot-melt extrusion: from theory to application in pharmaceutical formulation

H Patil, RV Tiwari, MA Repka - Aaps Pharmscitech, 2016 - Springer
Hot-melt extrusion (HME) is a promising technology for the production of new chemical
entities in the developmental pipeline and for improving products already on the market. In …

[HTML][HTML] Eudragit®: A Versatile Family of Polymers for Hot Melt Extrusion and 3D Printing Processes in Pharmaceutics

J Dos Santos, GS da Silva, MC Velho, RCR Beck - Pharmaceutics, 2021 - mdpi.com
Eudragit® polymers are polymethacrylates highly used in pharmaceutics for the
development of modified drug delivery systems. They are widely known due to their …

Systematic screening of pharmaceutical polymers for hot melt extrusion processing: A comprehensive review

R Thakkar, R Thakkar, A Pillai, EA Ashour… - International journal of …, 2020 - Elsevier
Pharmaceutical research, whether industrial or academic, has attempted to adopt
approaches most efficient for the development of innovations. With the abundance of …

Contribution of hot-melt extrusion technology to advance drug delivery in the 21st century

RV Tiwari, H Patil, MA Repka - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Hot-melt extrusion (HME) technology is applied successfully in the plastic,
rubber and food industry. HME has also emerged as an important technology for drug …

Melt extrusion: process to product

MA Repka, S Shah, J Lu, S Maddineni… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Niche applicability and industrial adaptability have led hot melt extrusion (HME)
techniques to gain wide acceptance and have, therefore, solidified their place in the array of …

Clostridium difficile infection: molecular pathogenesis and novel therapeutics

A Rineh, MJ Kelso, F Vatansever… - Expert review of anti …, 2014 - Taylor & Francis
The Gram-positive anaerobic bacterium Clostridium difficile produces toxins A and B, which
can cause a spectrum of diseases from pseudomembranous colitis to C. difficile-associated …

[HTML][HTML] Non-oncologic applications of nanomedicine-based photo-therapy

SW Yoo, G Oh, JC Ahn, E Chung - Biomedicines, 2021 - mdpi.com
Phototherapy is widely applied to various human diseases. Nanomedicine-based
phototherapy can be classified into photodynamic therapy (PDT) and photothermal therapy …

Review of melt crystallization in the pharmaceutical field, towards crystal engineering and continuous process development

S Jia, Z Gao, N Tian, Z Li, J Gong, J Wang… - … Research and Design, 2021 - Elsevier
Crystallization is a significant unit operation in the pharmaceutical industry, and much
attention has been paid to solution crystallization in the few last decades. Melt crystallization …

Oral drug delivery research in Europe

RJ Mrsny - Journal of controlled release, 2012 - Elsevier
The oral delivery of drugs is considered by decision-makers in the pharmaceutical industry
to be the most appealing route of administration. This belief has led to the identification of …

[HTML][HTML] Tissue engineering and photodynamic therapy: A new frontier of science for clinical application-an up-to-date review

M Aires-Fernandes, CF Amantino… - … in Bioengineering and …, 2022 - frontiersin.org
Tissue engineering (TE) connects principles of life sciences and engineering to develop
biomaterials as alternatives to biological systems and substitutes that can improve and …