The Lipid Formulation Classification System Consortium is an industry–academia
collaboration, established to develop standardized in vitro methods for the assessment of …

Self-emulsifying drug delivery system (SEDDS) is an isotropic mixture of lipid, surfactant and
co-surfactant, which forms a fine emulsion when comes in contact of an aqueous medium …

The large number of drug candidates with poor dissolution characteristics seen in the past
decade, has fostered interest in so-called “enabling formulations”, ie, formulations which …

Objectives This review highlights aspects of drug hydrophobicity and lipophilicity as
determinants of different oral formulation approaches with specific focus on enabling …

The delivery of drugs through the oral route is regarded as most optimal to achieve desired
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …

Lipid-based formulations, in particular supersaturated lipid-based formulations, are
important delivery approaches when formulating challenging compounds, as especially low …

Microemulsions and nanoemulsions are lipid-based pharmaceutical systems with a high
potential to increase the permeation of drugs through the skin. Although being isotropic …

Lipid-based formulations (LBFs) have demonstrated a great potential in enhancing the oral
absorption of poorly water-soluble drugs. However, construction of in vitro and in vivo …

Introduction: Poor aqueous solubility of active pharmaceutical ingredients (APIs) is one of
the main challenges in the development of new small molecular drugs. Additionally, the …

Self-emulsifying drug delivery systems (ie SEDDS, SMEDDS and SNEDDS) are widely
employed as solubility and bioavailability enhancing formulation strategies for poorly water …