Polymeric micelles provide a promising platform for improving oral absorption of poorly
soluble drugs. However, improved understanding of how drug retention within the …

The oral delivery efficiency of aged citrus peel extract containing polymethoxyflavones and 5-
demethylated polymethoxyflavones (PMFs) in three different systems, including a pure oil …

For over 20 years, stealth drug delivery has been synonymous with nanoparticulate
formulations and intravenous dosing. The putative determinants of stealth in these …

An increasing number of newly discovered drugs are poorly water-soluble and the use of
natural and synthetic lipids to improve the oral bioavailability of these drugs by utilizing the …

In this study we investigated lipolysis-triggered supersaturation and precipitation of a set of
model compounds formulated in lipid-based formulations (LBFs). The purpose was to …

Facing the increasing number of poorly water-soluble drugs, pharmaceutical scientists are
required to break new grounds for the delivery of these pharmaceutically problematic drugs …

The aim of this study was to develop and evaluate ultra-fine selfnanoemulsifying drug
delivery system (UF-SNEDDS) of meloxicam (MLX) to enhance its transdermal delivery. The …

Nanoemulsions (NEs) as multi-compartmentalized systems are extensively considered as
versatile drug delivery systems, due to their multifunctional and tuneable physicochemical …

Curcumin (CC), a potential antimalarial drug, has poor water solubility, stability and oral
bioavailability. To circumvent these pitfalls, lipid-based drug delivery systems (LBDDSs) with …

Aim The aim of the present study was to develop zeta potential changing self-emulsifying
drug delivery systems (SEDDS) via a flip-flop mechanism in order to improve their mucus …