Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer
N Khansari, Y Shakiba… - Recent patents on …, 2009 - ingentaconnect.com
Chronic inflammation is a pathological condition characterized by continued active
inflammation response and tissue destruction. Many of the immune cells including …
inflammation response and tissue destruction. Many of the immune cells including …
Caught up in a Wnt storm: Wnt signaling in cancer
The Wnt signaling pathway, named for its most upstream ligands, the Wnts, is involved in
various differentiation events during embryonic development and leads to tumor formation …
various differentiation events during embryonic development and leads to tumor formation …
Chronic inflammation and oxidative stress in human carcinogenesis
A Federico, F Morgillo, C Tuccillo… - … journal of cancer, 2007 - Wiley Online Library
A wide array of chronic inflammatory conditions predispose susceptible cells to neoplastic
transformation. In general, the longer the inflammation persists, the higher the risk of cancer …
transformation. In general, the longer the inflammation persists, the higher the risk of cancer …
[HTML][HTML] Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases
D Panigrahy, A Gartung, J Yang… - The Journal of …, 2019 - Am Soc Clin Investig
Cancer therapy is a double-edged sword, as surgery and chemotherapy can induce an
inflammatory/immunosuppressive injury response that promotes dormancy escape and …
inflammatory/immunosuppressive injury response that promotes dormancy escape and …
The roles of polyphenols in cancer chemoprevention
KW Lee, HJ Lee - Biofactors, 2006 - Wiley Online Library
Oxidative stress imposed by reactive oxygen species (ROS) plays a crucial role in the
pathophysiology associated with neoplasia, atherosclerosis, and neurodegenerative …
pathophysiology associated with neoplasia, atherosclerosis, and neurodegenerative …
Implications of oxidative stress and cell membrane lipid peroxidation in human cancer (Spain)
P Cejas, E Casado, C Belda-Iniesta, J De Castro… - Cancer Causes & …, 2004 - Springer
Abstract Reactive Oxygen Species (ROS) result from cell metabolism as well as from
extracellular processes. ROS exert some functions necessary for cell homeostasis …
extracellular processes. ROS exert some functions necessary for cell homeostasis …
Cyclooxygenases in the skin: pharmacological and toxicological implications
JL Lee, H Mukhtar, DR Bickers, L Kopelovich… - Toxicology and applied …, 2003 - Elsevier
Cyclooxygenase (COX), a prostaglandin-endoperoxide synthase (PTGS), catalyzes the
formation of prostaglandins from arachidonic acid. Prostaglandins are lipid signaling …
formation of prostaglandins from arachidonic acid. Prostaglandins are lipid signaling …
Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies
OJ Park, YJ Surh - Toxicology letters, 2004 - Elsevier
A wide array of antioxidative and anti-inflammatory substances derived from edible plants
have been reported to possess chemopreventive and chemoprotective activities. Among the …
have been reported to possess chemopreventive and chemoprotective activities. Among the …
[HTML][HTML] Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer
The essential fatty acids, linoleic acid and arachidonic acid play an important role in
pancreatic cancer development and progression. These fatty acids are metabolized to …
pancreatic cancer development and progression. These fatty acids are metabolized to …
COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells
ZL Li, SB Ye, LY OuYang, H Zhang, YS Chen… - …, 2015 - Taylor & Francis
The expansion of myeloid-derived suppressor cells (MDSCs) is a common feature of cancer,
but its biological roles and molecular mechanism remain unclear. Here, we investigated a …
but its biological roles and molecular mechanism remain unclear. Here, we investigated a …