The phase problem in X-ray crystallography arises from the fact that only the intensities, and
not the phases, of the diffracting electromagnetic waves are measured directly. Molecular …

Amyloid peptides are known to self-assemble into larger aggregates that are linked to the
pathogenesis of many neurodegenerative disorders. In contrast to primary nucleation, recent …

The field of tissue engineering is poised to be positively influenced by the advent of
supramolecular biopolymers, because of their promising tailorability coming from the bottom …

Since the advent of hybridoma technology in the year 1975, it took a decade to witness the
first approved monoclonal antibody Orthoclone OKT39 (muromonab-CD3) in the year 1986 …

The increasingly pressing demand of novel bio-drugs (eg, gene therapies) with
unprecedented levels of personalization, has put a remarkable pressure on the traditionally …

Structural proteomics identifies three-dimensional (3D) protein structures at an atomic
resolution on a genome-wide scale to better understand the interaction among protein …

Conventional broad-spectrum antibiotics synthesized through microbial secondary
metabolism with non-degradable residues can often accumulate in the environments, lead …

Alzheimer's disease is closely linked to the aggregation of Abeta42 peptides, which follow a
complex pathway involving primary nucleation and secondary processes. While previous …

Proteins serve as the machinery for cellular function. Proteins and protein complexes help
cellular systems maintain homeostasis and respond to environmental cues. Proper protein …

Globular proteins are linear chains of amino acids that after adopting a dominant single
three-dimensional structure, are the driving forces behind most cellular processes. Proteins …