CryoRhodopsins: a comprehensive characterization of a group of microbial rhodopsins from cold environments

GHU Lamm, E Marin, A Alekseev, AV Schellbach… - bioRxiv, 2024 - biorxiv.org
Microbial rhodopsins are omnipresent on Earth, however the vast majority of them remain
uncharacterized. Here we describe a new rhodopsin group from cold-adapted organisms …

The oxytocin-modulated brain circuit that synchronizes heart rate with breathing

JGM Buron, AA Linossier, C Gestreau, F Schaller… - bioRxiv, 2023 - biorxiv.org
The variation in heart rate in phase with breathing, called respiratory sinus arrhythmia
(RSA), is cardio-protective. RSA amplitude provides an index of health and physical fitness …

Two-Wavelength Computational Holography for Aberration-Corrected Simultaneous Optogenetic Stimulation and Inhibition of In Vitro Biological Samples

F Schmieder, L Büttner, T Hanitzsch, V Busskamp… - Applied Sciences, 2022 - mdpi.com
Optogenetics is a versatile toolset for the functional investigation of excitable cells such as
neurons and cardiomyocytes in vivo and in vitro. While monochromatic illumination of these …

A Silicon Neural Probe Monolithically Integrated with 20 µm-Pitched Dual-Color Micro-Led Arrays

D Mao, F Sun, B Driscoll, Z Li… - 2024 IEEE 37th …, 2024 - ieeexplore.ieee.org
Optogenetics is a powerful neuromodulation strategy that features temporal precision, cell-
type specificity, and bi-directionality (ie the capability to excite and inhibit the same neurons …

Organic dyes in optogenetics

A Penzkofer, P Hegemann… - Organic Lasers and …, 2024 - iopscience.iop.org
This chapter is an authoritative and extensive review on the use of organic dyes in the new
and exciting field of optogenetics. The authors begin by outlining the essence of …

Revealing the Oligomerization of Channelrhodopsin-2 in the Cell Membrane using Photo-Activated Localization Microscopy

E Bestsennaia, I Maslov, T Balandin, A Alekseev… - bioRxiv, 2023 - biorxiv.org
Microbial rhodopsins are retinal membrane proteins that found a broad application in
optogenetics. The oligomeric state of rhodopsins is important for their functionality and …

Robust Optogenetic Inhibition with Red-light-sensitive Anion-conducting Channelrhodopsins

J Oppermann, A Rozenberg, T Fabrin… - bioRxiv, 2023 - biorxiv.org
Channelrhodopsins (ChRs) are light-gated ion channels that are widely used to optically
activate or silence electrogenic cells such as neurons. Here, we describe the identification …

Non-Hebbian plasticity produces long-lasting associative memories

I Faress, V Khalil, WH Hou, A Moreno, N Andersen… - bioRxiv, 2023 - biorxiv.org
The dominant models of learning and memory, such as Hebbian plasticity, propose that
experiences are transformed into memories through input-specific synaptic plasticity at the …

Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heart.

T Stuedemann, B Schwarzova, T Schneidewind… - bioRxiv, 2023 - biorxiv.org
Transplantation of pluripotent stem cell-derived cardiomyocytes is a novel promising cell-
based therapeutic approach for patients with heart failure. However, engraftment …

cFos ensembles in the dentate gyrus rapidly segregate over time and do not form a stable map of space

PJ Lamothe-Molina, A Franzelin, L Beck, D Li… - bioRxiv, 2020 - biorxiv.org
Transgenic cFos reporter mice are used to identify and manipulate neurons that store
contextual information during fear learning. It is not clear, however, how spatial information …