Naringenin: A potential flavonoid phytochemical for cancer therapy

M Motallebi, M Bhia, HF Rajani, I Bhia, H Tabarraei… - Life Sciences, 2022 - Elsevier
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

Naringenin as a potential immunomodulator in therapeutics

W Zeng, L Jin, F Zhang, C Zhang, W Liang - Pharmacological research, 2018 - Elsevier
Naringenin, a citrus flavonoid that possesses various biological activities, has emerged as a
potential therapeutic agent for the management of a variety of diseases. Studies using cell …

Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update

R Joshi, YA Kulkarni, S Wairkar - Life sciences, 2018 - Elsevier
Phenolic compounds constitute one of the important classes of secondary metabolites in the
plants. Flavonoids are primary phenolic compounds found in natural drugs. Naringenin is a …

Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent

A Rauf, MA Shariati, M Imran, K Bashir… - … Science and Pollution …, 2022 - Springer
Though the incidence of several cancers in Western societies is regulated wisely, some
cancers such as breast, lung, and colorectal cancer are currently rising in many low-and …

Copper (II) complexes with naringenin and hesperetin: cytotoxic activity against A 549 human lung adenocarcinoma cells and investigation on the mode of action

LV Tamayo, LR Gouvea, AC Sousa, RM Albuquerque… - Biometals, 2016 - Springer
Abstract Copper (II) complexes [Cu (H 2 O) 2 (L1)(phen)](ClO 4)(1) and [Cu (H 2
O)(L2)(phen)](ClO 4)(2)(HL1= naringenin; HL2= hesperetin) were obtained, in which an …

Naringenin and hesperidin as promising alternatives for prevention and co-adjuvant therapy for breast cancer

MB Madureira, VM Concato, EMS Cruz… - Antioxidants, 2023 - mdpi.com
Citrus (genus Citrus L.) fruits are essential sources of bioactive compounds with antioxidant
properties, such as flavonoids. These polyphenolic compounds are divided into subclasses …

Mixed ligand complexes of Co (II), Ni (II) and Cu (II) with quercetin and diimine ligands: Synthesis, characterization, anti-cancer and anti-oxidant activity

H Mutlu Gençkal, M Erkisa, P Alper, S Sahin… - JBIC Journal of …, 2020 - Springer
In this work, mixed ligand complexes of Co (II) Ni (II) and Cu (II) were synthesized using
quercetin and diimine (1, 10-phenanthroline or 2, 2′-bipyiridine) ligands. The obtained Ni …

[HTML][HTML] Identification of potential therapeutic target of naringenin in breast cancer stem cells inhibition by bioinformatics and in vitro studies

A Hermawan, M Ikawati, RI Jenie, A Khumaira… - Saudi Pharmaceutical …, 2021 - Elsevier
Cancer therapy is a strategic measure in inhibiting breast cancer stem cell (BCSC)
pathways. Naringenin, a citrus flavonoid, was found to increase breast cancer cells' …

Naringenin induces intrinsic and extrinsic apoptotic signaling pathways in cancer cells: A systematic review and meta-analysis of in vitro and in vivo data

F Faramarzi, M Alimohammadi, A Rahimi… - Nutrition Research, 2022 - Elsevier
Various reports show the beneficial effect of naringenin on the development of cancer. We
hypothesized that naringenin suppresses cancer cells by activating intrinsic and extrinsic …

Citrus flavonoid naringenin reduces mammary tumor cell viability, adipose mass, and adipose inflammation in obese ovariectomized mice

JY Ke, T Banh, YH Hsiao, RM Cole… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Obesity‐related metabolic dysregulation may be a link between obesity and
postmenopausal breast cancer. Naringenin, a flavonoid abundant in grapefruits, displays …