Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …

In recent years, the development of 3D organoids has opened new avenues of investigation
into development, physiology, and regenerative medicine. Organoid formation and the …

Development of the metanephric kidney is strongly dependent on complex signaling
pathways and cell–cell communication between at least four major progenitor cell …

Directed differentiation of human pluripotent stem cells (hPSCs) uses a growing number of
small molecules and growth factors required for in vitro generation of renal lineage cells …

The kidney is one of the most important organs for maintaining body fluid homeostasis and
excretion of metabolic wastes. Three-dimensional (3D) biofabrication of kidney with …

Kidney organoids—3D representations of kidneys made either from pluripotent or tissue
stem cells—have been available for well over a decade. Their application could confer …

As an advance laboratory model, three‐dimensional (3D) organoid culture has recently
been recruited to study development, physiology and abnormality of kidney tissue. Micro …

Abstract Background Mesenchymal stem cells (MSCs) are multipotent stem cells that are
able to differentiate into multiple lineages including bone, cartilage, muscle and fat. They …

Kidney Disease (KD), has a high global prevalence and accounts for one of the most
prominent causes of morbidity and mortality in the twenty-first century. Despite the advances …

Acute kidney injury (AKI) is a common severe acute syndrome caused by multiple factors
and is characterized by a rapid decline in renal function during a short period. Bone marrow …