Nanoparticles: attractive tools to treat colorectal cancer

NK Younis, R Roumieh, EP Bassil… - Seminars in Cancer …, 2022 - Elsevier
Colorectal Cancer (CRC) is one of the leading causes of cancer-related deaths worldwide.
Despite the notable advances achieved over the last few decades, CRC remains a hard-to …

Nanomedicines inhibiting tumor metastasis and recurrence and their clinical applications

X Kong, R Cheng, J Wang, Y Fang, KC Hwang - Nano Today, 2021 - Elsevier
Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …

Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines

L Chen, H Qin, R Zhao, X Zhao, L Lin, Y Chen… - Science translational …, 2021 - science.org
Cancer vaccines based on resected tumors from patients have gained great interest as an
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …

Mechanisms of chemotherapeutic resistance and the application of targeted nanoparticles for enhanced chemotherapy in colorectal cancer

Y Guo, M Wang, Y Zou, L Jin, Z Zhao, Q Liu… - Journal of …, 2022 - Springer
Colorectal cancer is considered one of the major malignancies that threaten the lives and
health of people around the world. Patients with CRC are prone to post-operative local …

Polymeric and non-polymeric oxaliplatin nanomedicine for cancer therapy: A comprehensive review

M Pourmadadi, M Shaghaghi, R Arshad… - European Polymer …, 2024 - Elsevier
The importance of polymeric and non-polymeric Oxaliplatin (OXA) nanomedicine in cancer
therapy takes center stage in this article. OXA, a chemotherapy agent deployed in the …

Nano-enhanced immunotherapy: Targeting the immunosuppressive tumor microenvironment

Y Jin, Y Huang, H Ren, H Huang, C Lai, W Wang… - Biomaterials, 2024 - Elsevier
The tumor microenvironment (TME), which is mostly composed of tumor cells, immune cells,
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …

[HTML][HTML] Inhibition of murine colorectal cancer metastasis by targeting M2-TAM through STAT3/NF-kB/AKT signaling using macrophage 1-derived extracellular vesicles …

TG de Carvalho, P Lara, C Jorquera-Cordero… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer is still unmanageable despite advances in target therapy. However,
extracellular vesicles (EVs) have shown potential in nanomedicine as drug delivery systems …

Fabrication and assessment of folic acid conjugated-chitosan modified PLGA nanoparticle for delivery of alpha terpineol in colon cancer

A Rahmati, M Homayouni Tabrizi… - Journal of Biomaterials …, 2022 - Taylor & Francis
The objective of this study was to fabrication of α-terpineol-PLGA nanoparticles coated with
folic acid-chitosan (αT-PCF-NPs) as well as evaluates their anticancer effects. αT-PCF-NPs …

Functionalized nanoparticles targeting tumor-associated macrophages as cancer therapy

Y He, RF de Araújo Júnior, LJ Cruz, C Eich - Pharmaceutics, 2021 - mdpi.com
The tumor microenvironment (TME) plays a central role in regulating antitumor immune
responses. As an important part of the TME, alternatively activated type 2 (M2) macrophages …

[HTML][HTML] Retinoids as anti-cancer agents and their mechanisms of action

Y Jin, SS Teh, HLN Lau, J Xiao… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Retinoids (vitamin A) have been reported extensively for anti-cancer properties due to their
high receptor-binding affinities and gene regulation abilities. However, the anti-cancer …