A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …

RA associates with an increased burden of cardiovascular disease, which is at least partially
attributed to classical risk factors such as hypertension (HT) and dyslipidaemia. HT is highly …

Objectives: The purpose of this study was to test the hypothesis that a small heart coupled
with reduced blood volume contributes to the postural orthostatic tachycardia syndrome …

The sympathetic nervous system plays a key role in regulating arterial blood pressure in
humans. This review provides an overview of sympathetic neural control of the circulation …

Endovascular renal nerve ablation has been developed to treat resistant hypertension. In
addition to lowering efferent renal sympathetic activation, the intervention may attenuate …

There is growing evidence to suggest that many disease states are accompanied by chronic
elevations in sympathetic nerve activity. The present review will specifically focus on central …

Recent animal studies have reported that exercise pressor reflex (EPR)-mediated increases
in blood pressure are exaggerated in hypertensive (HTN) rodents. Whether these findings …

Elevated large-artery stiffness is recognized as an independent predictor of cardiovascular
and all-cause mortality. The mechanisms responsible for such stiffening are incompletely …

Because of resetting, a role for baroreflexes in long-term control of arterial pressure has
been commonly dismissed in the past. However, in recent years, this perspective has …

Essential hypertension is a multifactorial disorder with a strong genetic predisposition.
Although anti-hypertensive medications have drastically reduced cardiovascular diseases …