Statin toxicity: mechanistic insights and clinical implications
NC Ward, GF Watts, RH Eckel - Circulation research, 2019 - Am Heart Assoc
There is now overwhelming evidence to support lowering LDL-c (low-density lipoprotein
cholesterol) to reduce cardiovascular morbidity and mortality. Statins are a class of drugs …
cholesterol) to reduce cardiovascular morbidity and mortality. Statins are a class of drugs …
Side effects of statins: from pathophysiology and epidemiology to diagnostic and therapeutic implications
Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …
reductase, has proven beneficial preventive effects on cardiovascular events. However …
Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry
SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …
Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care
GF Watts, SS Gidding, P Mata, J Pang… - Nature Reviews …, 2020 - nature.com
Optimal care for familial hypercholesterolaemia (FH) requires patient-centred management,
multidisciplinary teamwork, involvement of primary care practitioners, patient networks …
multidisciplinary teamwork, involvement of primary care practitioners, patient networks …
[HTML][HTML] Cholesterol lowering drugs
KR Feingold - 2016 - europepmc.org
There are currently eight different classes of drugs available for lowering cholesterol levels.
There are currently seven HMG-CoA reductase inhibitors (statins) approved for lowering …
There are currently seven HMG-CoA reductase inhibitors (statins) approved for lowering …
Borneol in cardio-cerebrovascular diseases: pharmacological actions, mechanisms, and therapeutics
S Liu, Y Long, S Yu, D Zhang, Q Yang, Z Ci… - Pharmacological …, 2021 - Elsevier
With the coming acceleration of global population aging, the incidence rate of cardio-
cerebrovascular diseases (CVDs) is increasing. It has become the leading cause of human …
cerebrovascular diseases (CVDs) is increasing. It has become the leading cause of human …
The role of pharmacogenomics in adverse drug reactions
R Cacabelos, N Cacabelos, JC Carril - Expert Review of Clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern
worldwide. There are multiple causes of ADRs, some of which are preventable …
worldwide. There are multiple causes of ADRs, some of which are preventable …
Preparation and evaluation of atorvastatin-loaded nanoemulgel on wound-healing efficacy
Tissue repair and wound healing are complex processes that involve inflammation,
granulation, and remodeling of the tissue. The potential of various statins including …
granulation, and remodeling of the tissue. The potential of various statins including …
Polysaccharides from medicine and food homology materials: a review on their extraction, purification, structure, and biological activities
J Xu, J Zhang, Y Sang, Y Wei, X Chen, Y Wang, H Xue - Molecules, 2022 - mdpi.com
Medicine and food homology (MFH) materials are rich in polysaccharides, proteins, fats,
vitamins, and other components. Hence, they have good medical and nutritional values …
vitamins, and other components. Hence, they have good medical and nutritional values …
Nonadherence to lipid‐lowering therapy and strategies to improve adherence in patients with atherosclerotic cardiovascular disease
NR Desai, M Farbaniec, DG Karalis - Clinical Cardiology, 2023 - Wiley Online Library
Despite the availability of effective therapies that lower low‐density lipoprotein cholesterol
(LDL‐C) levels in patients with atherosclerotic cardiovascular disease, many eligible …
(LDL‐C) levels in patients with atherosclerotic cardiovascular disease, many eligible …