[HTML][HTML] Tauvid™: the first FDA-approved PET tracer for imaging tau pathology in Alzheimer's disease

CVML Jie, V Treyer, R Schibli, L Mu - Pharmaceuticals, 2021 - mdpi.com
Tauvid has been approved by the US Food and Drug Administration (FDA) in 2020 for
positron emission tomography (PET) imaging of adult patients with cognitive impairments …

Sex differences in dementia with Lewy bodies: Focused review of available evidence and future directions

SY Chiu, KA Wyman-Chick, TJ Ferman… - Parkinsonism & related …, 2023 - Elsevier
In this review, we summarize the current knowledge on sex differences in dementia with
Lewy bodies (DLB) relating to epidemiology, clinical features, neuropathology, biomarkers …

[HTML][HTML] Fluid and biopsy based biomarkers in Parkinson's disease

DG Coughlin, DJ Irwin - Neurotherapeutics, 2023 - Elsevier
Several advances in fluid and tissue-based biomarkers for use in Parkinson's disease (PD)
and other synucleinopathies have been made in the last several years. While work …

Plasma biomarkers of neurodegeneration in mild cognitive impairment with Lewy bodies

CA Hamilton, J O'Brien, A Heslegrave… - Psychological …, 2023 - cambridge.org
BackgroundBlood biomarkers of Alzheimer's disease (AD) may allow for the early detection
of AD pathology in mild cognitive impairment (MCI) due to AD (MCI-AD) and as a co …

Longitudinal atrophy in prodromal dementia with Lewy bodies points to cholinergic degeneration

K Kantarci, Z Nedelska, Q Chen, ML Senjem… - Brain …, 2022 - academic.oup.com
Mild cognitive impairment with the core clinical features of dementia with Lewy bodies is
recognized as a prodromal stage of dementia with Lewy bodies. Although grey matter …

Dementia with Lewy bodies: Impact of co‐pathologies and implications for clinical trial design

JB Toledo, C Abdelnour, RS Weil… - Alzheimer's & …, 2023 - Wiley Online Library
Dementia with Lewy bodies (DLB) is clinically defined by the presence of visual
hallucinations, fluctuations, rapid eye movement (REM) sleep behavioral disorder, and …

[HTML][HTML] Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient selection and biomarkers

LL Gibson, C Abdelnour, J Chong… - Current Opinion in …, 2023 - journals.lww.com
Clinical trials in dementia with Lewy bodies: the evolving c... : Current Opinion in Neurology
Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient …

(Dis‐) Connected dots in dementia with lewy bodies—a systematic review of connectivity studies

A Habich, LO Wahlund, E Westman… - Movement …, 2023 - Wiley Online Library
Studies on dementia with Lewy bodies (DLB) have mainly focused on the degeneration of
distinct cortical and subcortical regions related to the deposition of Lewy bodies. In view of …

Advances in dementia with Lewy bodies

MJ Armstrong - Therapeutic Advances in Neurological …, 2021 - journals.sagepub.com
Dementia with Lewy bodies (DLB) is a clinical diagnosis representing a specific
presentation of a pathological α-synucleinopathy (Lewy body disease). DLB is one entity …

[HTML][HTML] Bidirectional relationship between sleep disturbances and Parkinson's disease

EN Minakawa - Frontiers in Neurology, 2022 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). Both diseases share common clinical and pathological features …