The bone marrow side of axial spondyloarthritis
Spondyloarthritis (SpA) is characterized by the infiltration of innate and adaptive immune
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …
Why inhibition of IL-23 lacked efficacy in ankylosing spondylitis
The term spondyloarthritis pertains to both axial and peripheral arthritis including ankylosing
spondylitis (AS) and psoriatic arthritis (PsA), which is strongly linked to psoriasis and also …
spondylitis (AS) and psoriatic arthritis (PsA), which is strongly linked to psoriasis and also …
Genetically proxied IL‐13 inhibition is associated with risk of psoriatic disease: Mendelian randomization study
Objective Inhibitors of the IL‐13 pathway, such as dupilumab, are licensed for atopic
dermatitis and asthma. Adverse events resembling psoriatic disease after dupilumab …
dermatitis and asthma. Adverse events resembling psoriatic disease after dupilumab …
From bed to bench and back: TNF-α, IL-23/IL-17A, and JAK-dependent inflammation in the pathogenesis of psoriatic synovitis
Psoriatic arthritis (PsA) is a chronic inflammatory immune-mediated disease with a
burdensome impact on quality of life and substantial healthcare costs. To date …
burdensome impact on quality of life and substantial healthcare costs. To date …
The potential role of genetics, environmental factors, and gut dysbiosis in the aberrant non-coding RNA expression to mediate inflammation and osteoclastogenic …
HT Liao, CY Tsai, CC Lai, SC Hsieh, YS Sun… - Frontiers in cell and …, 2022 - frontiersin.org
Ankylosing spondylitis (AS) or radiographic axial spondyloarthritis is a chronic immune-
mediated rheumatic disorder characterized by the inflammation in the axial skeleton …
mediated rheumatic disorder characterized by the inflammation in the axial skeleton …
Bone Involvement in Rheumatoid Arthritis and Spondyloartritis: An Updated Review
F Orsini, C Crotti, G Cincinelli, R Di Taranto, A Amati… - Biology, 2023 - mdpi.com
Simple Summary Chronic inflammatory arthritis, such as rheumatoid arthritis (RA) and
spondyloarthritis (SpA), often have a significant impact on bone tissue, where bone is not …
spondyloarthritis (SpA), often have a significant impact on bone tissue, where bone is not …
Characterization of a Musculoskeletal Syndrome of Enthesitis and Arthritis in Patients With Atopic Dermatitis Treated With Dupilumab, an Interleukin‐4/13 Inhibitor
CD Hughes, J Nathan, L Mathew, AE Pink… - Arthritis & …, 2023 - Wiley Online Library
Objective To characterize the presentation and outcomes of patients with atopic dermatitis
(AD) who developed musculoskeletal symptoms after treatment with dupilumab, a human …
(AD) who developed musculoskeletal symptoms after treatment with dupilumab, a human …
Osteoimmunology of Spondyloarthritis
A Fassio, F Atzeni, M Rossini, V D'Amico… - International Journal of …, 2023 - mdpi.com
The mechanisms underlying the development of bone damage in the context of
spondyloarthritis (SpA) are not completely understood. To date, a considerable amount of …
spondyloarthritis (SpA) are not completely understood. To date, a considerable amount of …
[HTML][HTML] Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation
J Krstić, S Mojsilović, SS Mojsilović… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Bone regeneration is a tightly regulated process that ensures proper repair and functionality
after injury. The delicate balance between bone formation and resorption is governed by …
after injury. The delicate balance between bone formation and resorption is governed by …
[HTML][HTML] Network pharmacology analysis and animal experiment validation of neuroinflammation inhibition by total ginsenoside in treating CSM
Z Li, Y Dai, Z Wu, G Li, P Pu, C Hu, L Zhou, K Zhu… - Phytomedicine, 2024 - Elsevier
Background Cervical spondylotic myelopathy (CSM) is a degenerative pathology that affects
both upper and lower extremity mobility and sensory function, causing significant pressure …
both upper and lower extremity mobility and sensory function, causing significant pressure …