Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world. Sustained hepatic inflammation is a key driver of the transition from simple fatty liver …

Mouse hepatitis virus (MHV) is a positive-strand RNA virus that causes an acute
encephalomyelitis that later resolves into a chronic fulminating demyelinating disease …

Intracerebral infection of mice with mouse hepatitis virus, a member of the Coronaviridae
family, reproducibly results in an acute encephalomyelitis that progresses to a chronic …

The detection of nucleic acids by the innate immune system is an essential host response
during viral infection. In recent years, a number of immune sensors capable of recognizing …

As the coronavirus disease 2019 (COVID-19) pandemic continues to be a multidimensional
threat to humanity, more evidence of neurological involvement associated with it has …

Natural killer (NK) cells are potent effector cells of the innate immune system possessing
both cytotoxic and immunoregulatory capabilities, which contribute to their crucial role in …

ABSTRACT CD4 T cell activation during peripheral infections not only is essential in
inducing protective CD8 T cell memory but also promotes CD8 T cell function and survival …

Rationale: Immune cells play an important role during the generation and resolution of
thrombosis. T cells are powerful regulators of immune and nonimmune cell function …

The local production of gamma interferon (IFN-γ) is important to control Toxoplasma gondii
in the brain, but the basis for these protective effects is not fully understood. The studies …

Human immunodeficiency virus (HIV) is the chief contributor to global burden of disease. In
2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages …