Intratumoral immunotherapy: using the tumour against itself

MR Crittenden, U Thanarajasingam, RG Vile… - …, 2005 - Wiley Online Library
Diverse immunotherapy approaches have achieved success in controlling individual
aspects of immune responses in animal models. Transfer of such immunotherapies to …

[HTML][HTML] The CC chemokine ligand 3 regulates CD11c+ CD11b+ CD8α− dendritic cell maturation and activation following viral infection of the central nervous system …

MJ Trifilo, TE Lane - Virology, 2004 - Elsevier
The role of CC chemokine ligand 3 (CCL3) in activation of dendritic cells (DCs) following
mouse hepatitis virus (MHV) infection of the central nervous system (CNS) was examined …

[HTML][HTML] More than a key—the pathological roles of SARS-CoV-2 spike protein in COVID-19 related cardiac injury

Z Lin - Sports Medicine and Health Science, 2023 - Elsevier
Cardiac injury is common in hospitalized coronavirus disease 2019 (COVID-19) patients
and cardiac abnormalities have been observed in a significant number of recovered COVID …

[HTML][HTML] Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs

Y Shen, J Iqbal, L Xiao, RC Lynch, A Rosenwald… - BMC immunology, 2004 - Springer
Background There are three major B-cell compartments in peripheral lymphoid organs: the
germinal center (GC), the mantle zone (MNZ) and the marginal zone (MGZ). Unique sets of …

Host Genetic Impact on Infectious Diseases among Different Ethnic Groups

L Naidoo, T Arumugam, V Ramsuran - Advanced Genetics, 2023 - Wiley Online Library
Infectious diseases such as malaria, tuberculosis (TB), human immunodeficiency virus (HIV),
and the coronavirus disease of 2019 (COVID‐19) are problematic globally, with high …

[HTML][HTML] Mast cell stabilizer ketotifen fumarate reverses inflammatory but not neuropathic-induced mechanical pain in mice

CB Meloto, P Ingelmo, EV Perez, R Pitt… - Pain …, 2021 - journals.lww.com
Objective: We aimed to test the effect of treatment with KF in pain assays in mice and in a
case series of patients with chronic widespread pain. Methods: The analgesic effect of KF …

[HTML][HTML] TLR3 signaling promotes the induction of unique human BDCA-3 dendritic cell populations

NJ Colletti, H Liu, AC Gower, YO Alekseyev… - Frontiers in …, 2016 - frontiersin.org
Conventional and plasmacytoid dendritic cells (cDCs and pDCs) are the two populations of
DCs that can be readily identified in human blood. Conventional DCs have been subdivided …

[HTML][HTML] Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome

E Pollenus, H Possemiers, S Knoops, F Prenen… - Plos …, 2024 - journals.plos.org
Plasmodium parasites cause malaria, a global health disease that is responsible for more
than 200 million clinical cases and 600 000 deaths each year. Most deaths are caused by …

[HTML][HTML] Differential roles of CCL2 and CCR2 in host defense to coronavirus infection

KS Held, BP Chen, WA Kuziel, BJ Rollins, TE Lane - Virology, 2004 - Elsevier
The CC chemokine ligand 2 (CCL2, monocyte chemoattractant protein-1) is important in
coordinating the immune response following microbial infection by regulating T cell …

Single-cell analysis reveals macrophage-driven T cell dysfunction in severe COVID-19 patients

X Liu, A Zhu, J He, Z Chen, L Liu, Y Xu, F Ye, H Feng… - MedRxiv, 2020 - medrxiv.org
The vastly spreading COVID-19 pneumonia is caused by SARS-CoV-2. Lymphopenia and
cytokine levels are tightly associated with disease severity. However, virus-induced immune …