[HTML][HTML] Macrophage/microglia polarization for the treatment of diabetic retinopathy

Y Yao, J Li, Y Zhou, S Wang, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Macrophages/microglia are immune system defense and homeostatic cells that develop
from bone marrow progenitor cells. According to the different phenotypes and immune …

Potential of mesenchymal stem cell-derived conditioned medium/secretome as a therapeutic option for ocular diseases

WH Bouche Djatche, H Zhu, W Ma, Y Li, Z Li… - Regenerative …, 2023 - Taylor & Francis
Research has shown that the therapeutic effect of mesenchymal stem cells (MSCs) is
partially due to its secreted factors as opposed to the implantation of the cells into the treated …

[HTML][HTML] Human mesenchymal stem cell therapy promotes retinal ganglion cell survival and target reconnection after optic nerve crush in adult rats

AJ da Silva-Junior, LA Mesentier-Louro… - Stem Cell Research & …, 2021 - Springer
Background Optic-nerve injury results in impaired transmission of visual signals to central
targets and leads to the death of retinal ganglion cells (RGCs) and irreversible vision loss …

[HTML][HTML] Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing

YR Neupane, HK Handral, SA Alkaff, WH Chng… - … Pharmaceutica Sinica B, 2023 - Elsevier
Wound healing is a dynamic process that involves a series of molecular and cellular events
aimed at replacing devitalized and missing cellular components and/or tissue layers …

[HTML][HTML] Shaping the microglia in retinal degenerative diseases using stem cell therapy: practice and prospects

N Jin, W Sha, L Gao - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Retinal degenerative disease (RDD) refers to a group of diseases with retinal degeneration
that cause vision loss and affect people's daily lives. Various therapies have been proposed …

[HTML][HTML] Current development, obstacle and futural direction of induced pluripotent stem cell and mesenchymal stem cell treatment in degenerative retinal disease

MC Chiang, E Chern - International Journal of Molecular Sciences, 2022 - mdpi.com
Degenerative retinal disease is one of the major causes of vision loss around the world. The
past several decades have witnessed emerging development of stem cell treatment for …

Research progress on co-culture and application of mesenchymal stem cells and nerve cells

LIU Ming-Yi, ZB ZHANG, SHI Jia-Yue… - Jie Fang Jun Yi Xue …, 2022 - search.proquest.com
Co-culture is an important technique to study specific biological problems, and has been
widely applied recent years in the field of nervous system diseases which are characterized …