Oxidative stress, inflammation and colorectal cancer: An overview

A Bardelčíková, J Šoltys, J Mojžiš - Antioxidants, 2023 - mdpi.com
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

Role of Akkermansia in Human Diseases: From Causation to Therapeutic Properties

A Pellegrino, G Coppola, F Santopaolo, A Gasbarrini… - Nutrients, 2023 - mdpi.com
The gut microbiota plays a critical role in the modulation of host metabolism and immune
response, and its impairment has been implicated in many gastrointestinal and …

Microbiome confounders and quantitative profiling challenge predicted microbial targets in colorectal cancer development

RY Tito, S Verbandt, M Aguirre Vazquez, L Lahti… - Nature medicine, 2024 - nature.com
Despite substantial progress in cancer microbiome research, recognized confounders and
advances in absolute microbiome quantification remain underused; this raises concerns …

Intestinal microbiota and miRNA in IBD: a narrative review about discoveries and perspectives for the future

ECS Oliveira, AEV Quaglio, DO Magro… - International Journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC)
and comprises a chronic gastrointestinal tract disorder characterized by hyperactive and …

[HTML][HTML] Obesity-induced thymic involution and cancer risk

MK Lagou, GS Karagiannis - Seminars in Cancer Biology, 2023 - Elsevier
Declining thymic functions associated either with old age (ie, age-related thymic involution),
or with acute involution as a result of stress, infectious disease, or cytoreductive therapies …

Risk of cancer in patients with inflammatory bowel diseases and keys for patient management

V Laredo, S García-Mateo, SJ Martínez-Domínguez… - Cancers, 2023 - mdpi.com
Simple Summary Inflammatory Bowel Diseases (IBDs) are increasingly prevalent
pathologies due to the rise in incidence in some geographic areas and the improvement in …

The controversial role of intestinal mast cells in colon cancer

R Molfetta, R Paolini - Cells, 2023 - mdpi.com
Mast cells are tissue-resident sentinels involved in large number of physiological and
pathological processes, such as infection and allergic response, thanks to the expression of …

Nad+ Precursors and intestinal inflammation: therapeutic insights involving gut microbiota

J Niño-Narvión, MI Rojo-López, P Martinez-Santos… - Nutrients, 2023 - mdpi.com
The oxidized form of nicotinamide adenine dinucleotide (NAD+) is a critical metabolite for
living cells. NAD+ may act either as a cofactor for many cellular reactions as well as a …

Microbiome modulation in inflammatory diseases: Progress to microbiome genetic engineering

F Mousavinasab, R Karimi, S Taheri… - Cancer Cell …, 2023 - Springer
Recent developments in sequencing technology and analytical approaches have allowed
researchers to show that the healthy gut microbiome is very varied and capable of …

[HTML][HTML] Photodynamic therapy for inflammatory and cancerous diseases of the intestines: molecular mechanisms and prospects for application

B Deng, K Wang, L Zhang, Z Qiu, W Dong… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a minimally invasive treatment that effectively targets cancer
and inflammatory diseases. It has gained recognition for its efficacy, low toxicity, and …