Quercetin: its main pharmacological activity and potential application in clinical medicine

D Yang, T Wang, M Long, P Li - Oxidative Medicine and …, 2020 - Wiley Online Library
Quercetin is a flavonoid compound widely present in plants and exhibits a variety of
biological activities. Research on quercetin has shown its potential for medical application …

Important flavonoids and their role as a therapeutic agent

A Ullah, S Munir, SL Badshah, N Khan, L Ghani… - Molecules, 2020 - mdpi.com
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …

Role of intestinal microbiota in the bioavailability and physiological functions of dietary polyphenols

K Kawabata, Y Yoshioka, J Terao - Molecules, 2019 - mdpi.com
Polyphenols are categorized as plant secondary metabolites, and they have attracted much
attention in relation to human health and the prevention of chronic diseases. In recent years …

A review of classification, biosynthesis, biological activities and potential applications of flavonoids

S Chen, X Wang, Y Cheng, H Gao, X Chen - Molecules, 2023 - mdpi.com
Flavonoids represent the main class of plant secondary metabolites and occur in the tissues
and organs of various plant species. In plants, flavonoids are involved in many biological …

Recent discoveries of anticancer flavonoids

D Raffa, B Maggio, MV Raimondi, F Plescia… - European journal of …, 2017 - Elsevier
In this review we report the recent advances in anticancer activity of the family of natural
occurring flavonoids, covering the time span of the last five years. The bibliographic data will …

Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

E Zaplatic, M Bule, SZA Shah, MS Uddin, K Niaz - Life sciences, 2019 - Elsevier
Quercetin belongs to the flavonoids family, which is present in most of the plants including
fruits, vegetables, green tea and even in red wine having antioxidant activities. It is available …

Cellular senescence: from mechanisms to current biomarkers and senotherapies

V Lucas, C Cavadas, CA Aveleira - Pharmacological Reviews, 2023 - ASPET
An increase in life expectancy in developed countries has led to a surge of chronic aging-
related diseases. In the last few decades, several studies have provided evidence of the …

Natural coumarins from two cultivars of watermelon seeds as biosafe anticancer agents, an algorithm for their isolation and evaluation

YF Mustafa, RN Ismael, RM Jebir - Journal of Molecular Structure, 2024 - Elsevier
The seeds of two watermelon cultivars–allsweet and princess–were explored in this study as
sources of potential biosafe natural antioxidant and anticancer agents. In the first algorithmic …

Quercetin and its metabolites inhibit recombinant human angiotensin-converting enzyme 2 (ACE2) activity

X Liu, R Raghuvanshi, FD Ceylan… - Journal of agricultural …, 2020 - ACS Publications
Angiotensin-converting enzyme 2 (ACE2) is a host receptor for severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Inhibiting the interaction between the envelope …

Antidiabetic effect of quercetin: A systematic review and meta-analysis of animal studies

M Bule, A Abdurahman, S Nikfar, M Abdollahi… - Food and chemical …, 2019 - Elsevier
Quercetin is a plant polyphenol with biological activities such as anti-inflammatory,
anticancer, antidiabetic, neuroprotective and anti-allergic. The objective of this review is to …