We care, therefore we are: anesthesia-related morbidity and mortality: the 46th Rovenstine Lecture
JE Cottrell - The Journal of the American Society of …, 2008 - pubs.asahq.org
EMERY Andrew Rovenstine, MD (Professor, Department of Anesthesiology, New York
University, New York; 1895–1960), was a giant in the founding of our specialty, and I feel …
University, New York; 1895–1960), was a giant in the founding of our specialty, and I feel …
Subclinical carbon monoxide limits apoptosis in the developing brain after isoflurane exposure
Y Cheng, RJ Levy - Anesthesia & Analgesia, 2014 - journals.lww.com
BACKGROUND: Volatile anesthetics cause widespread apoptosis in the developing brain.
Carbon monoxide (CO) has antiapoptotic properties, and exhaled endogenous CO is …
Carbon monoxide (CO) has antiapoptotic properties, and exhaled endogenous CO is …
Inhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
M Iketani, M Hatomi, Y Fujita… - Journal of …, 2024 - Wiley Online Library
Inhalation of hydrogen (H2) gas is therapeutically effective for cerebrovascular diseases,
neurodegenerative disorders, and neonatal brain disorders including pathologies induced …
neurodegenerative disorders, and neonatal brain disorders including pathologies induced …
The protective effect of notoginsenoside R1 on isoflurane-induced neurological impairment in the rats via regulating miR-29a expression and neuroinflammation
M Wang, H Liu, L Xu, M Li, M Zhao - Neuroimmunomodulation, 2022 - karger.com
Introduction: Isoflurane inhalation leads to apoptotic neurodegeneration and further results
in learning and cognitive dysfunction. Notoginsenoside R1 (NGR1), a major ingredient from …
in learning and cognitive dysfunction. Notoginsenoside R1 (NGR1), a major ingredient from …
[HTML][HTML] Astaxanthin reduces isoflurane-induced neuroapoptosis via the PI3K/Akt pathway
CM Wang, XL Cai, QP Wen - Molecular Medicine …, 2016 - spandidos-publications.com
Astaxanthin is an oxygen-containing derivative of carotenoids that effectively suppresses
reactive oxygen and has nutritional and medicinal value. The mechanisms underlying the …
reactive oxygen and has nutritional and medicinal value. The mechanisms underlying the …
Methodologic recommendations and possible interpretations of video‐EEG recordings in immature rodents used as experimental controls: A TASK1‐WG2 report of the …
The use of immature rodents to study physiologic aspects of cortical development requires
high‐quality recordings electroencephalography (EEG) with simultaneous video recording …
high‐quality recordings electroencephalography (EEG) with simultaneous video recording …
Carbon monoxide and anesthesia-induced neurotoxicity
RJ Levy - Neurotoxicology and teratology, 2017 - Elsevier
The majority of commonly used anesthetic agents induce widespread neuronal
degeneration in the developing mammalian brain. Downstream, the process appears to …
degeneration in the developing mammalian brain. Downstream, the process appears to …
Clinical research approaches to studying pediatric anesthetic neurotoxicity
Neuronal cell death after general anesthesia has recently been demonstrated in neonatal
animal models. The possibility of anesthesia-induced neurotoxicity during an uneventful …
animal models. The possibility of anesthesia-induced neurotoxicity during an uneventful …
The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain
SM Manning, G Boll, E Fitzgerald, DB Selip… - International Journal of …, 2011 - Elsevier
The N-methyl-d-aspartate glutamate receptor (NMDAR) has been implicated in preterm
brain injury (periventricular leukomalacia (PVL)) and represents a potential therapeutic …
brain injury (periventricular leukomalacia (PVL)) and represents a potential therapeutic …