Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Recent advances in nanotechnology-aided materials in combating microbial resistance and functioning as antibiotics substitutes

MU Munir, A Ahmed, M Usman… - International Journal of …, 2020 - Taylor & Francis
The ongoing escalation of drug-resistant bacteria creates the leading challenges for human
health. Current predictions show that deaths due to bacterial illness will be more in …

Sortase A: a model for transpeptidation and its biological applications

N Pishesha, JR Ingram… - Annual review of cell and …, 2018 - annualreviews.org
Molecular biologists and chemists alike have long sought to modify proteins with
substituents that cannot be installed by standard or even advanced genetic approaches. We …

Sortase transpeptidases: structural biology and catalytic mechanism

AW Jacobitz, MD Kattke, J Wereszczynski… - Advances in protein …, 2017 - Elsevier
Gram-positive bacteria use sortase cysteine transpeptidase enzymes to covalently attach
proteins to their cell wall and to assemble pili. In pathogenic bacteria sortases are potential …

[HTML][HTML] A review on pilus assembly mechanisms in Gram-positive and Gram-negative bacteria

T Shanmugasundarasamy, DK Govindarajan… - The Cell Surface, 2022 - Elsevier
The surface of Gram-positive and Gram-negative bacteria contains long hair-like
proteinaceous protrusion known as pili or fimbriae. Historically, pilin proteins were …

Adsorption of bacteriophages on bacterial cells

AV Letarov, EE Kulikov - Biochemistry (Moscow), 2017 - Springer
The biological functions of bacteriophage virions come down to the solution of three basic
problems: to provide protection of viral nucleic acid from the factors of extracellular …

Don't let sleeping dogmas lie: new views of peptidoglycan synthesis and its regulation

H Zhao, V Patel, JD Helmann, T Dörr - Molecular microbiology, 2017 - Wiley Online Library
Bacterial cell wall synthesis is the target for some of our most powerful antibiotics and has
thus been the subject of intense research focus for more than 50 years. Surprisingly, we still …

Testing association between soil bacterial diversity and soil carbon storage on the Loess Plateau

Y Yang, Y Dou, S An - Science of the Total Environment, 2018 - Elsevier
Bacteria are widely distributed and play an important role in soil carbon (C) cycling. The
impact of soil bacterial diversity on soil C storage has been well established, yet little is …

Evaluation of antimicrobial activity of ZnO based nanocomposites for the coating of non-critical equipment in medical-care facilities

AP Piedade, AC Pinho, R Branco, PV Morais - Applied Surface Science, 2020 - Elsevier
Nosocomial infections are quite common in medical facilities environment and the highest
percentage is caused by bacteria. The transmission of such infections is often made by …