A series of new 2-(4/3-substitutedbenzyl) thieno [2, 3-d] pyrimidin-4 (3 H)-ones (2a-f) and 2-
(4/3-substituted benzyl)-5, 6, 7, 8-tetrahydrobenzo [4, 5] thieno [2, 3-d] pyrimidin-4 (3 H)-one …

Cutaneous melanoma is one of the most common malignant skin tumors and advanced
melanoma is usually associated with a poor prognosis. In the current study, we …

One of the vital aspects of a cell is cell death to continue their normal cell turnover,
propagation, proper development, and the maintenance of the immune system. Cell death is …

溴结构域和超末端(BET) 家族是一类能特异性识别乙酰化赖氨酸调控基因转录过程的蛋白,
在多种疾病的发生发展中具有重要作用. 溴结构域蛋白4 (BRD4) 是BET 家族的一员 …

Although the proteins in bromodomain and extra-terminal domain (BET) family are
promising therapy drug targets for numerous human diseases, the binding effectiveness is …

В статье приводятся модифицированный метод синтеза 2-замещенных 5, 6, 7, 8-
тетрагидробензо [4, 5] тиено [2, 3-d] пиримидин-4 (3 H)-она и прогноз их …

The past four years which I feel were very short but also quite long during my PhD study and
were so precious time to let me learn a lot not only in my scientific life but also in my social …

Background: Qilongtian is a traditional Chinese medicine compound with Yunnan medical
characteristics. Its main components have the effect of inhibiting inflammation. Inflammatory …

The human genome is mainly transcribed into non-coding RNAs that are not translated into
proteins. With increasing understanding of function through continued research it has …

The functioning of the heart is determined by the extracellular matrix composing it and the
dynamic equilibrium of different types of cells. Different cardiovascular diseases such as …