Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

[HTML][HTML] Differentiated thyroid cancer—treatment: state of the art

B Schmidbauer, K Menhart, D Hellwig… - International journal of …, 2017 - mdpi.com
Differentiated thyroid cancer (DTC) is a rare malignant disease, although its incidence has
increased over the last few decades. It derives from follicular thyroid cells. Generally …

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

[HTML][HTML] Novel treatments for anaplastic thyroid carcinoma

SM Ferrari, G Elia, F Ragusa, I Ruffilli, C La Motta… - Gland …, 2020 - ncbi.nlm.nih.gov
Anaplastic thyroid cancer (ATC) is one of the deadliest human cancers and it is less than 2%
of thyroid carcinomas (TCs). The standard treatment of ATC includes surgical debulking …

Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer

F Panebianco, AV Nikitski, MN Nikiforova… - Cancer …, 2019 - Wiley Online Library
Background Reactivation of telomerase reverse transcriptase (TERT) is an important event
in cancer. Two hotspot mutations in the TERT promoter region, c.‐124C> T (C228T) and c …

M6A-mediated up-regulation of LncRNA LIFR-AS1 enhances the progression of pancreatic cancer via miRNA-150-5p/ VEGFA/Akt signaling

JQ Chen, YP Tao, YG Hong, HF Li, ZP Huang, XF Xu… - Cell Cycle, 2021 - Taylor & Francis
ABSTRACT N6-methyladenosine (m6A) modification, the most abundant internal
methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. There is …

[HTML][HTML] Differentiated thyroid carcinoma in pediatric age: genetic and clinical scenario

F Galuppini, F Vianello, S Censi, S Barollo… - Frontiers in …, 2019 - frontiersin.org
Introduction: Follicular-derived differentiated thyroid carcinoma (DTC) is the most common
endocrine and epithelial malignancy in children. The differences in the clinical and …

[HTML][HTML] BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node …

N Fakhruddin, M Jabbour, M Novy, H Tamim… - Scientific reports, 2017 - nature.com
Concordance between mutations in the primary papillary thyroid carcinoma (PTC) and the
paired x lymph node metastasis may elucidate the potential role of molecular targeted …

[HTML][HTML] Targeting EML4-ALK gene fusion variant 3 in thyroid cancer

MD Aydemirli, JDH van Eendenburg… - Endocrine-related …, 2021 - erc.bioscientifica.com
Finding targetable gene fusions can expand the limited treatment options in radioactive
iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line …

[HTML][HTML] Radiomics in predicting mutation status for thyroid cancer: A preliminary study using radiomics features for predicting BRAFV600E mutations in papillary …

JH Yoon, K Han, E Lee, J Lee, EK Kim, HJ Moon… - PloS one, 2020 - journals.plos.org
Purpose To evaluate whether if ultrasonography (US)-based radiomics enables prediction of
the presence of BRAFV600E mutations among patients diagnosed as papillary thyroid …