Intestinal microbiome shifts, dysbiosis, inflammation, and non-alcoholic fatty liver disease

ET Saltzman, T Palacios, M Thomsen… - Frontiers in …, 2018 - frontiersin.org
Adverse fluctuations in the distribution of the intestinal microbiome cohort has been
associated with the onset of intra-and extra-intestinal inflammatory conditions, like the …

Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease

W Jiang, N Wu, X Wang, Y Chi, Y Zhang, X Qiu, Y Hu… - Scientific reports, 2015 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has recently been considered to be under the
influence of the gut microbiota, which might exert toxic effects on the human host after …

Inhibition of cyclooxygenase-2 alleviates liver cirrhosis via improvement of the dysfunctional gut-liver axis in rats

JH Gao, SL Wen, H Tong, CH Wang… - American Journal …, 2016 - journals.physiology.org
Inflammatory transport through the gut-liver axis may facilitate liver cirrhosis.
Cyclooxygenase-2 (COX-2) has been considered as one of the important molecules that …

Lymphocyte Gene Expression Signatures from Patients and Mouse Models of Hereditary Hemochromatosis Reveal a Function of HFE as a Negative Regulator of CD8+ T …

M Costa, E Cruz, S Oliveira, V Benes, T Ivacevic… - PLoS …, 2015 - journals.plos.org
Abnormally low CD8+ T-lymphocyte numbers is characteristic of some patients with
hereditary hemochromatosis (HH), a MHC-linked disorder of iron overload. Both …

Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis

Y Lai, X Li, T Li, X Li, T Nyunoya, K Chen, G Kitsios… - Thorax, 2023 - thorax.bmj.com
Background One hallmark of sepsis is the reduced number of lymphocytes, termed
lymphopenia, that occurs from decreased lymphocyte proliferation or increased cell death …

[HTML][HTML] If blocking potency of ivabradine is preserved under elevated endotoxin levels in human atrial myocytes

S Scheruebel, CN Koyani, S Hallström, P Lang… - Journal of molecular and …, 2014 - Elsevier
Lower heart rate is associated with better survival in patients with multiple organ dysfunction
syndrome (MODS), a disease mostly caused by sepsis. The benefits of heart rate reduction …

Effects of Pasteurella multocida lipopolysaccharides on bovine leukocytes

S Periasamy, PE Praveena, N Singh - Microbial pathogenesis, 2018 - Elsevier
Lipopolysaccharide (LPS) is a major virulence factor of Gram-negative bacteria playing a
major role in stimulating protective immune response in mammalian host. However, in many …

Ultrastructural changes in endothelial cells of buffaloes following in-vitro exposure to Pasteurella multocida B:2

Y Puspitasari, A Salleh, M Zamri-Saad - BMC veterinary research, 2020 - Springer
Background Pasteurella multocida B: 2 causes haemorrhagic septicaemia in cattle and
buffaloes. However, buffaloes are found to be more susceptible to the infection than cattle …

[HTML][HTML] Probiotics and synbiotics targeting the intestinal microbiome attenuate non-alcoholic fatty liver disease

L Vitetta, JD Henson - Hepatobiliary Surgery and Nutrition, 2020 - ncbi.nlm.nih.gov
© HepatoBiliary Surgery and Nutrition. All rights reserved. HepatoBiliary Surg Nutr 2020; 9
(4): 526-529| http://dx. doi. org/10.21037/hbsn. 2019.11. 24 choline, trimethylamine is …

In-vitro phagocytosis and intracellular killing of Pasteurella multocida B: 2 by phagocytic cells of buffaloes

Y Puspitasari, S Annas, MN Adza-Rina… - Microbial …, 2019 - Elsevier
Pasteurella multocida B: 2 is a Gram-negative organism causing haemorrhagic septicaemia
(HS) in buffaloes. It causes severe pulmonary infection, leading to infiltration of numerous …