Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives
R Simo, C Hernández - Trends in Endocrinology & Metabolism, 2014 - cell.com
Diabetic retinopathy (DR), one of the leading causes of preventable blindness, has been
considered a microcirculatory disease of the retina. However, there is emerging evidence to …
considered a microcirculatory disease of the retina. However, there is emerging evidence to …
Neurovascular unit in diabetic retinopathy: pathophysiological roles and potential therapeutical targets
S Nian, ACY Lo, Y Mi, K Ren, D Yang - Eye and Vision, 2021 - Springer
Diabetic retinopathy (DR), one of the common complications of diabetes, is the leading
cause of visual loss in working-age individuals in many industrialized countries. It has been …
cause of visual loss in working-age individuals in many industrialized countries. It has been …
Retinal vascular endothelial cell dysfunction and neuroretinal degeneration in diabetic patients
M Mrugacz, A Bryl, K Zorena - Journal of clinical medicine, 2021 - mdpi.com
Diabetes mellitus (DM) has become a vital societal problem as epidemiological studies
demonstrate the increasing incidence of type 1 and type 2 diabetes. Lesions observed in the …
demonstrate the increasing incidence of type 1 and type 2 diabetes. Lesions observed in the …
[PDF][PDF] Age-related macular degeneration (AMD): pathogenesis and therapy
JZ Nowak - Pharmacological reports, 2006 - Citeseer
Age-related macular degeneration (AMD) is a disease leading to severe visual loss and
legal blindness in the elderly population. Its pathogenesis, likely multifactorial, involving a …
legal blindness in the elderly population. Its pathogenesis, likely multifactorial, involving a …
Diabetic macular ischaemia-a new therapeutic target?
Diabetic macular ischaemia (DMI) is traditionally defined and graded based on the
angiographic evidence of an enlarged and irregular foveal avascular zone. However, these …
angiographic evidence of an enlarged and irregular foveal avascular zone. However, these …
Wnt Signaling in vascular eye diseases
The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …
[HTML][HTML] The retinal pigmentation pathway in human albinism: Not so black and white
R Bakker, EL Wagstaff, CC Kruijt, E Emri… - Progress in retinal and …, 2022 - Elsevier
Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …
Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence
R Simo, C Hernandez - Progress in Retinal and eye Research, 2015 - Elsevier
Diabetic retinopathy remains as a leading cause of blindness in developed countries.
Current treatments target late stages of DR when vision has already been significantly …
Current treatments target late stages of DR when vision has already been significantly …
The innate immune system in diabetic retinopathy
WW Pan, F Lin, PE Fort - Progress in retinal and eye research, 2021 - Elsevier
The prevalence of diabetes has been rising steadily in the past half-century, along with the
burden of its associated complications, including diabetic retinopathy (DR). DR is currently …
burden of its associated complications, including diabetic retinopathy (DR). DR is currently …
Diabetic retinopathy–an underdiagnosed and undertreated inflammatory, neuro-vascular complication of diabetes
SH Sinclair, SS Schwartz - Frontiers in Endocrinology, 2019 - frontiersin.org
Diabetes mellitus is a world-wide epidemic and diabetic retinopathy, a devastating, vision-
threatening condition, is one of the most common diabetes-specific complications. Diabetic …
threatening condition, is one of the most common diabetes-specific complications. Diabetic …