Developing biomedical engineering technologies for reproductive medicine

Y Zhu, B Kong, R Liu, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …

The incompletely fulfilled promise of embryo transfer in cattle—why aren't pregnancy rates greater and what can we do about it?

PJ Hansen - Journal of Animal Science, 2020 - academic.oup.com
Typically, bovine embryos are transferred into recipient females about day 7 after estrus or
anticipated ovulation, when the embryo has reached the blastocyst stage of development …

The future of IVF: the new normal in human reproduction

VA Kushnir, GD Smith, EY Adashi - Reproductive Sciences, 2022 - Springer
Increased demand for in vitro fertilization (IVF) due to socio-demographic trends, and supply
facilitated by new technologies, converged to transform the way a substantial proportion of …

Organ-on-a-chip technology for the study of the female reproductive system

RE Young, DD Huh - Advanced drug delivery reviews, 2021 - Elsevier
Over the past decade, organs-on-a-chip and microphysiological systems have emerged as a
disruptive in vitro technology for biopharmaceutical applications. By enabling new …

Microfluidic in-vitro fertilization technologies: Transforming the future of human reproduction

Y Fang, R Wu, JM Lee, LHM Chan, KYJ Chan - TrAC Trends in Analytical …, 2023 - Elsevier
The field of assisted reproductive technology (ART) has seen constant improvement and
advancement targeted towards optimal development of the embryos in vitro to improve …

Advances of microfluidic technology in reproductive biology

A Nikshad, A Aghlmandi, R Safaralizadeh… - Life Sciences, 2021 - Elsevier
Abstract According to World Health Organization (WHO) reports about 70 million couples
suffer from infertility all over the world. A lot of research groups are working on this issue and …

A fully integrated biomimetic microfluidic device for evaluation of sperm response to thermotaxis and chemotaxis

Y Yan, B Zhang, Q Fu, J Wu, R Liu - Lab on a Chip, 2021 - pubs.rsc.org
In recent decades, humans have faced greater challenges in reproduction. Assisted
reproductive technology is the most prominent approach for addressing this problem …

A review on microfluidics: An aid to assisted reproductive technology

AB Alias, HY Huang, DJ Yao - Molecules, 2021 - mdpi.com
Infertility is a state of the male or female reproductive system that is defined as the failure to
achieve pregnancy even after 12 or more months of regular unprotected sexual intercourse …

Endometrial receptivity and embryo implantation in carnivores—commonalities and differences with other mammalian species

EE Paulson, P Comizzoli - Biology of reproduction, 2021 - academic.oup.com
Endometrial receptivity and embryo implantation processes are a major point of pregnancy
failure in many mammalian species, including humans. Although reproductive biology in …

Microfluidic aspiration-assisted electrical impedance spectroscopy system is a reliable tool for the characterization of oocyte hardening

Y Cao, J Floehr, D Azarkh, U Schnakenberg - Sensors and Actuators B …, 2023 - Elsevier
The fertilization rate in assisted reproduction depends significantly on the quality of the
oocyte, especially on the hardening of the zona pellucida, which is a gelatinous layer of …