[HTML][HTML] Drug‑resistant Acinetobacter baumannii: From molecular mechanisms to potential therapeutics

HJ Wu, ZG Xiao, XJ Lv, HT Huang… - Experimental and …, 2023 - spandidos-publications.com
Bacterial drug resistance is increasingly becoming an important problem that needs to be
solved urgently in modern clinical practices. Infection caused by Acinetobacter baumannii is …

[HTML][HTML] Virulence Factors and Pathogenicity Mechanisms of Acinetobacter baumannii in Respiratory Infectious Diseases

Y Yao, Q Chen, H Zhou - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii (A. baumannii) has become a notorious pathogen causing
nosocomial and community-acquired infections, especially ventilator-associated …

[HTML][HTML] Increased ompW and ompA expression and higher virulence of Acinetobacter baumannii persister cells

BL Schmitt, BF Leal, M Leyser, MP de Barros… - BMC microbiology, 2023 - Springer
Background Acinetobacter baumannii is one of the main causes of healthcare-associated
infections that threaten public health, and carbapenems, such as meropenem, have been a …

Transcriptional activation of ompA in Neisseria gonorrhoeae mediated by the XRE family member protein NceR

CL Holley, V Dhulipala, SA Maurakis, AN Greenawalt… - Mbio, 2023 - Am Soc Microbiol
Increasing antibiotic resistance of Neisseria gonorrhoeae, the causative agent of gonorrhea,
is a growing global concern that has renewed vaccine development efforts. The gonococcal …

L-Serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

J Zhou, D Feng, X Li, Y Chen, M Zhang… - Microbiology …, 2024 - Am Soc Microbiol
The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of
patients and seriously affects their prognosis, which motivates us to explore novel ways to …

Anti-OmpA antibodies as potential inhibitors of Acinetobacter baumannii biofilm formation, adherence to, and proliferation in A549 human alveolar epithelial cells

H Barati, Z Fekrirad, MJ Nadoushan, I Rasooli - Microbial Pathogenesis, 2024 - Elsevier
Outer membrane protein A (OmpA) is a critical virulence factor in Acinetobacter baumannii,
influencing adhesion, biofilm formation, host immune response, and host cell apoptosis. We …

[HTML][HTML] Antibacterial activity and mechanism of X33 antimicrobial oligopeptide against Acinetobacter baumannii

Q Lu, X Wu, Y Fang, Y Wang, B Zhang - Synthetic and Systems …, 2024 - Elsevier
Acinetobacter baumannii is a pathogenic bacterium widespread in human environments,
especially in intensive care units, and is associated with high morbidity and infection rates …

Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow‐derived dendritic cells involving the PI3K/mTOR pathway

H Tan, L Cao - Immunity, Inflammation and Disease, 2023 - Wiley Online Library
Background Outer membrane protein A (OmpA) is the major virulence factor of
Acinetobacter baumannii and plays a wide role in the pathogenesis and antimicrobial …