Dominant Analytical Techniques in DNA Nanotechnology for Various Applications

K Neyra, HR Everson, D Mathur - Analytical Chemistry, 2024 - ACS Publications
DNA nanotechnology is rapidly gaining traction in numerous applications, each bearing
varying degrees of tolerance to the quality and quantity necessary for viable nanostructure …

Multiplexed DNA and Protease Detection with Orthogonal Energy Transfer on a Single Quantum Dot Scaffolded Biosensor

DA Hastman, S Hooe, M Chiriboga, SA Díaz… - ACS …, 2023 - ACS Publications
Almost all pathogens, whether viral or bacterial, utilize key proteolytic steps in their
pathogenesis. The ability to detect a pathogen's genomic material along with its proteolytic …

Purification of DNA Nanoparticles Using Photocleavable Biotin Tethers

HR Everson, K Neyra, DV Scarton… - … Applied Materials & …, 2024 - ACS Publications
The number of applications of self-assembled deoxyribonucleic acid (DNA) origami
nanoparticles (DNA NPs) has increased drastically, following the development of a variety of …

Effect of hydrophilicity-imparting substituents on exciton delocalization in squaraine dye aggregates covalently templated to DNA Holliday junctions

G Pascual, SK Roy, G Barcenas, CK Wilson… - Nanoscale, 2024 - pubs.rsc.org
Molecular aggregates exhibit emergent properties, including the collective sharing of
electronic excitation energy known as exciton delocalization, that can be leveraged in …

Sculpting photoproducts with DNA origami

J Gorman, SM Hart, T John, MA Castellanos, D Harris… - Chem, 2024 - cell.com
Natural light-harvesting systems spatially organize densely packed dyes in different
configurations to either transport excitons or convert them into charged photoproducts, with …

[HTML][HTML] DNA-Based Fluorescent Nanoprobe for Cancer Cell Membrane Imaging

X Wu, X Shuai, K Nie, J Li, L Liu, L Wang, C Huang… - Molecules, 2024 - mdpi.com
As an important barrier between the cytoplasm and the microenvironment of the cell, the cell
membrane is essential for the maintenance of normal cellular physiological activities. An …

[HTML][HTML] Sequestration within peptide coacervates improves the fluorescence intensity, kinetics, and limits of detection of dye-based DNA biosensors

CM Green, D Sementa, D Mathur, JS Melinger… - Communications …, 2024 - nature.com
Peptide-based liquid-liquid phase separated domains, or coacervates, are a biomaterial
gaining new interest due to their exciting potential in fields ranging from biosensing to drug …

Proximity-Induced Bipedal DNA Walker for Accurately Visualizing microRNA in Living Cancer Cell

X Feng, X Bi, J Feng, S Hu, Y Wang, S Zhao… - Analytical …, 2024 - ACS Publications
DNA walker, a type of dynamic DNA device that is capable of moving progressively along
prescribed walking tracks, has emerged as an ideal and powerful tool for biosensing and …

Single‐Molecule Assessment of DNA Hybridization Kinetics on Dye‐Loaded DNA Nanostructures

C Li, Y Xie, X Cheng, L Xu, G Yao, Q Li, J Shen, C Fan… - Small, 2024 - Wiley Online Library
DNA nanostructures offer a versatile platform for precise dye assembly, making them
promising templates for creating photonic complexes with applications in photonics and …

Minimizing Structural Heterogeneity in DNA Self-Assembled Dye Templating via DNA Origami-Tuned Conformations

K Cervantes-Salguero, M Kadrmas, BM Ward… - Langmuir, 2024 - ACS Publications
With recent advances in DNA-templated dye aggregation for leveraging and engineering
molecular excitons, a need exists for minimizing structural heterogeneity. Holliday Junction …