Biochemical verification of tobacco use and abstinence: 2019 update

NL Benowitz, JT Bernert, J Foulds… - Nicotine and …, 2020 - academic.oup.com
Background The changing prevalence and patterns of tobacco use, the advent of novel
nicotine delivery devices, and the development of new biomarkers prompted an update of …

Biomarkers of exposure to secondhand and thirdhand tobacco smoke: recent advances and future perspectives

S Torres, C Merino, B Paton, X Correig… - International journal of …, 2018 - mdpi.com
Smoking is the leading preventable disease worldwide and passive smoking is estimated to
be the cause of about 1.0% of worldwide mortality. The determination of tobacco smoke …

Biomarkers of exposure to new and emerging tobacco delivery products

SF Schick, BC Blount, P Jacob 3rd… - … of Physiology-Lung …, 2017 - journals.physiology.org
Accurate and reliable measurements of exposure to tobacco products are essential for
identifying and confirming patterns of tobacco product use and for assessing their potential …

Exposure and metabolic activation biomarkers of carcinogenic tobacco-specific nitrosamines

SS Hecht, I Stepanov, SG Carmella - Accounts of chemical …, 2016 - ACS Publications
Conspectus Lung cancer is the leading cause of cancer death in the world, and cigarette
smoking is its main cause. Oral cavity cancer is another debilitating and often fatal cancer …

Biomarkers of tobacco exposure: summary of an FDA-sponsored public workshop

CM Chang, SH Edwards, A Arab… - … Biomarkers & Prevention, 2017 - AACR
Since 2009, the FDA Center for Tobacco Products (CTP) has had the authority to regulate
the manufacturing, distribution, and marketing of tobacco products in order to reduce the …

[HTML][HTML] Biomarkers of exposure in environment-wide association studies–Opportunities to decode the exposome using human biomonitoring data

N Steckling, A Gotti, S Bose-O'Reilly, D Chapizanis… - Environmental …, 2018 - Elsevier
Abstract Background The European Union's 7th Framework Programme (EU's FP7) project
HEALS–Health and Environment-wide Associations based on Large Population Surveys …

Reduction in exposure to selected harmful and potentially harmful constituents approaching those observed upon smoking abstinence in smokers switching to the …

C Haziza, G de La Bourdonnaye… - Nicotine and …, 2020 - academic.oup.com
Abstract Introduction The Tobacco Heating System (THS) is a “heat-not-burn” tobacco
product designed to generate significantly lower levels of harmful and potentially harmful …

Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program

JP Buckley, ES Barrett, PI Beamer… - Journal of exposure …, 2020 - nature.com
Abstract The Environmental Influences on Child Health Outcomes (ECHO) Program will
evaluate environmental factors affecting children's health (perinatal, neurodevelopmental …

LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner

T Bian, Y Wang, JF Botello, Q Hu, Y Jiang, A Zingone… - Oncogene, 2022 - nature.com
LKB1 loss of function is one key oncogenic event in lung cancer. Clinical data suggest that
LKB1 loss of function is associated with patients' smoking status. The responsible …

Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress

MR Chao, MS Cooke, CY Kuo, CH Pan, HH Liu… - Environment …, 2018 - Elsevier
Background Worldwide, smoking is a major public health problem, with exposure to
environmental tobacco smoke (ETS) affecting both smokers, and passive smokers, including …