Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a …

T Shi, DA McAllister, KL O'Brien, EAF Simoes… - The Lancet, 2017 - thelancet.com
Background We have previously estimated that respiratory syncytial virus (RSV) was
associated with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) …

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

NI Mazur, D Higgins, MC Nunes, JA Melero… - The Lancet Infectious …, 2018 - thelancet.com
The global burden of disease caused by respiratory syncytial virus (RSV) is increasingly
recognised, not only in infants, but also in older adults (aged≥ 65 years). Advances in …

[PDF][PDF] Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic interventions

MJ Bunders, M Altfeld - Immunity, 2020 - cell.com
Men present more frequently with severe manifestations of coronavirus disease 2019
(COVID-19) and are at higher risk for death. The underlying mechanisms for these …

Respiratory syncytial virus–associated hospitalizations among young children: 2015–2016

B Rha, AT Curns, JY Lively, AP Campbell… - …, 2020 - publications.aap.org
BACKGROUND: Respiratory syncytial virus (RSV) is a major cause of hospitalized acute
respiratory illness (ARI) among young children. With RSV vaccines and immunoprophylaxis …

Respiratory syncytial virus: infection, detection, and new options for prevention and treatment

C Griffiths, SJ Drews, DJ Marchant - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

During the COVID‐19 pandemic where has respiratory syncytial virus gone?

G Di Mattia, R Nenna, E Mancino, V Rizzo… - Pediatric …, 2021 - Wiley Online Library
The diffusion of the SARS‐CoV‐2 virus and the implementation of restrictive measures led to
a drastic reduction of respiratory syncytial virus (RSV) diffusion. Few RSV cases have been …

Role of viral infections in the development and exacerbation of asthma in children

T Jartti, JE Gern - Journal of allergy and clinical immunology, 2017 - Elsevier
Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …

[HTML][HTML] Epidemiology and prevention of respiratory syncytial virus infections in children in Italy

C Azzari, E Baraldi, P Bonanni, E Bozzola… - Italian journal of …, 2021 - Springer
Respiratory syncytial virus (RSV) is the leading global cause of respiratory infections in
infants and the second most frequent cause of death during the first year of life. This highly …

[HTML][HTML] Otitis media

AGM Schilder, T Chonmaitree, AW Cripps… - Nature reviews Disease …, 2016 - nature.com
Otitis media (OM) or middle ear inflammation is a spectrum of diseases, including acute otitis
media (AOM), otitis media with effusion (OME;'glue ear') and chronic suppurative otitis media …