Cognitive dysfunction in fibromyalgia patients has been reported, especially when increased
attentional demands are required. Transcranial direct current stimulation (tDCS) over the …

Chronic pain is a constantly recurring and persistent illness, presenting a formidable
healthcare challenge for patients and physicians alike. Current first‐line analgesics offer …

The therapeutic effects of centrally acting pharmaceuticals can manifest gradually and
unreliably in patients, making the drug discovery process slow and expensive. Biological …

Fibromyalgia is characterized by chronic widespread pain and several additional symptoms
such as fatigue, cognitive dysfunction, depressive episodes, and anxiety. The underlying …

Fibromyalgia is a chronic complex syndrome of non-articulate origin characterized by
musculoskeletal pain, painful tender points, sleep problems and co-morbidities including …

Neural functioning and plasticity can be studied on different levels of organization and
complexity ranging from the molecular and synaptic level to neural circuitry of whole brain …

The relationship between glutamate and g-aminobutyric acid (GABA) levels in the living
human brain and pain sensitivity is unknown. Combined glutamine/glutamate (Glx), as well …

OBJECTIVES: The paradoxical development of chronic abdominal pain is an
underrecognized side effect of opioid use. Narcotic bowel syndrome (NBS), occurring in only …

Pain can be elicited through all mammalian sensory pathways yet cross-modal sensory
integration, and its relationship to clinical pain, is largely unexplored. Centralized chronic …

Despite the intense research on developing new therapies for neuropathic pain states,
available treatments have limited efficacy and unfavorable safety profiles. Epigenetic …