Much success has been achieved with platinum-based chemotherapeutic agents, ie through
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …

Abstract Positron Emission Tomography (PET) is a nuclear medicine imaging technique that
is widely used in early detection and treatment follow up of many diseases, including cancer …

Microfluidic devices fabricated using poly (dimethylsiloxane)(PDMS) polymer are routinely
used for in vitro cell culture for a wide range of cellular assays. These assays typically …

The aim of this review is to provide an overview of the contributions and recent advances
made by Iranian scientists in the field of isocyanide-based reactions between 1999 and …

Cytochrome P450 2C9 (CYP2C9) is one of the most abundant CYP enzymes in the human
liver. CYP2C9 metabolizes more than 100 therapeutic drugs, including tolbutamide …

Epilepsy is a common neurological disorder worldwide and anti-epileptic drugs (AEDs) are
always the first choice for treatment. However, more than 50% of patients with epilepsy who …

After the development of “classical” tricyclic antidepressants and monoamine oxidase
inhibitors, numerous other classes of antidepressant drugs have been introduced onto the …

Autoinjectors are self-injectable devices; they are important class of medical devices which
can deliver drugs through subcutaneous or intramuscular route. They enclose prefilled …

Introduction: Anxiety disorders are considered the most common mental disorders and they
can increase the risk for comorbid mood and substance use disorders, significantly …

Objective This review summarizes the therapeutic potential of midazolam as an
anticonvulsant antidote for organophosphate (OP) intoxication. Methods Benzodiazepines …