Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell
death characterized by iron-dependence and the accumulation of lipid peroxidation that …

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

Accumulating evidence has highlighted the role of ferroptosis, a novel type of programmed
cell death involved in the pathological process of myocardial infarction (MI). However, the …

BACKGROUND: The membrane components of cardiomyocytes are rich in polyunsaturated
fatty acids, which are easily oxidized. Thus, an efficient glutathione-based lipid redox system …

Iron overload increases the production of harmful reactive oxygen species in the Fenton
reaction, which causes oxidative stress in the body and lipid peroxidation in the cell …

Susceptibility to myocardial ischemia-reperfusion (IR) injury in type-2 diabetes (T2DM)
remains disputed, although studies have reported that ferroptosis is associated with …

HJ11 is a novel traditional Chinese medicine developed from the appropriate addition and
reduction of Si-Miao-Yong-An decoction, which has been commonly used to treat ischemia …

Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …