Prenatal exposure to inorganic arsenic (iAs) has been associated with adverse
developmental and reproductive outcomes. These outcomes may be tied to altered …

Arsenic exposure is associated with a plethora of age-related health outcomes of disparate
etiology. However, evidence of the impact of arsenic on aging remains limited. Here, we …

Background Infants born extremely premature are at increased risk for health complications
later in life for which neonatal inflammation may be a contributing biological driver. Placental …

Inorganic arsenic (iAs) is one of the largest toxic exposures to impact humanity worldwide.
Exposure to iAs during pregnancy may disrupt the proper remodeling of the epigenome of …

Arsenic is a relatively abundant metalloid that impacts DNA methylation and has been
implicated in various adverse health outcomes including several cancers and diabetes …

A biological mechanism by which exposure to environmental contaminants results in gene-
specific CpG methylation patterning is currently unknown. We hypothesize that gene-specific …

The epigenome is a dynamic mediator of gene expression that shapes the way that cells,
tissues, and organisms respond to their environment. Initial studies in the emerging field of …

The field of epigenetics represents the study of the collection of potentially heritable changes
in gene expression resulting from modifications “above”(epi-) the genome (genetics) …

Early-life exposure to arsenic increases risk of developing a variety of non-malignant and
malignant diseases. Arsenic-induced carcinogenesis may be mediated through epigenetic …

Benzene is a broadly used industrial chemicals which causes various hematologic
abnormalities in human. Altered DNA methylation has been proposed as epigenetic …