Objective Exposure to heavy metals has been reported to be associated with impaired
cognitive function, but the underlying mechanisms remain unclear. This pilot study aimed to …

There is increasing evidence that environmental agents mediate susceptibility to infectious
disease. Studies support the impact of prenatal/early life exposure to the environmental …

Arsenic is a known potent risk factor for bladder cancer. Increasing evidence suggests that
epigenetic alterations, eg, DNA methylation and histones posttranslational modifications …

Arsenic (As) contamination in groundwater is responsible for numerous adverse health
outcomes among millions of people. Epigenetic alterations are among the most widely …

Adverse environmental exposures in pregnancy can significantly alter the development of
the fetus resulting in impaired child neurodevelopment. Such exposures can lead to …

Background Exposure to polybrominated diphenyl ethers (PBDEs) may influence risk of
developing post-menopausal breast cancer. Although mechanisms are poorly understood …

Arsenic, a carcinogen with immunotoxic effects, is a common contaminant of drinking water
and certain food worldwide. We hypothesized that chronic arsenic exposure alters gene …

Almost all species show sexual discordance in many traits and diseases. DNA methylation is
known to contribute to these differences through well-established mechanisms including X …

Increased methylation levels at cytosines proximal to guanines (CpG) in the promoter
regions of tumor suppressor genes have been reported to play an important role in the …

Chronic exposure to inorganic arsenic (iAs) has been linked to diabetic phenotypes in both
humans and mice. However, diabetogenic effects of iAs exposure during specific …