[HTML][HTML] Prenatal and postnatal exposure to polystyrene microplastics induces testis developmental disorder and affects male fertility in mice

T Zhao, L Shen, X Ye, G Bai, C Liao, Z Chen… - Journal of Hazardous …, 2023 - Elsevier
Polystyrene microplastics (PS-MPs) can threaten human health, especially male fertility.
However, most existing studies have focused on the adulthood stage of male reproduction …

Abnormalities of pubertal development and gonadal function in Noonan syndrome

G Patti, M Scaglione, NG Maiorano, G Rosti… - Frontiers in …, 2023 - frontiersin.org
Background Noonan syndrome (NS) is a genetic multisystem disorder characterised by
variable clinical manifestations including dysmorphic facial features, short stature …

MAPKs signaling is obligatory for male reproductive function in a development-specific manner

L Kumar, S Solanki, A Jain, M Botts, R Gupta… - … in Reproductive Health, 2024 - frontiersin.org
Mitogen-activated protein kinases (MAPKs) represent widely expressed and evolutionarily
conserved proteins crucial for governing signaling pathways and playing essential roles in …

[HTML][HTML] Puerarin improves busulfan-induced disruption of spermatogenesis by inhibiting MAPK pathways

HT Li, K Zhong, YF Xia, J Song, XQ Chen… - Biomedicine & …, 2023 - Elsevier
Male infertility is a global concern, with a noticeable increase in the decline of
spermatogenesis and sperm quality. However, there are limited clinically effective …

Heat wave exposure and semen quality in sperm donation volunteers: A retrospective longitudinal study in south China

X Deng, Q Wang, C Shi, J Wei, Z Lv, S Huang… - Environmental …, 2023 - Elsevier
Background Previous studies have suggested an association between non-optimum
ambient temperature and decreased semen quality. However, the effect of exposure to heat …

Inhibition of p38MAPK signalling pathway alleviates radiation‐induced testicular damage through improving spermatogenesis

J Yang, X Ou, M Shu, J Wang, X Zhang… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Damage to the testis following exposure to ionizing
radiation has become an urgent problem to be solved. Here we have investigated if …

The Role of G3BP1 Gene Mediates P38 MAPK/JNK Pathway in Testicular Spermatogenic Dysfunction Caused by Cyfluthrin

XY Li, J Sun, LY Ma, YX Xie, N Zhang, J Zhao, HF Yang - Toxics, 2023 - mdpi.com
In recent years, male infertility has received global attention and seriously affected the
quality of human fertility, and pyrethroids (type II pyrethroids), as recognized environmental …

N-3 PUFA deficiency from early life to adulthood exacerbated susceptibility to reactive oxygen species-induced testicular dysfunction in adult mice

YC Zhao, CC Wang, JY Yang, XY Li… - Journal of Agricultural …, 2023 - ACS Publications
Homeostasis of reactive oxygen species is required to maintain sperm maturation and
capacitation. Docosahexaenoic acid (DHA) is accumulated in testicles and spermatozoa …

Unveiling the Genetic Complexity of Teratozoospermia: Integrated Genomic Analysis Reveals Novel Insights into lncRNAs' Role in Male Infertility

MA Kyrgiafini, T Giannoulis, A Chatziparasidou… - International Journal of …, 2023 - mdpi.com
Male infertility is a global health issue, affecting over 20 million men worldwide. Genetic
factors are crucial in various male infertility forms, including teratozoospermia. Nonetheless …

Involvement of Sep38β in the Insecticidal Activity of Bacillus thuringiensis against Beet Armyworm, Spodoptera exigua (Lepidoptera)

Y Ji, B Gao, D Zhao, Y Wang, L Zhang… - Journal of Agricultural …, 2024 - ACS Publications
The p38 mitogen-activated protein kinases (MAPKs) are associated with insect immunity,
tissue repair, and the insecticidal activity of Bacillus thuringiensis (Bt). Here, a p38 MAPK …