Butyrate producers,“The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …
The immunomodulatory functions of butyrate
MT Siddiqui, GAM Cresci - Journal of inflammation research, 2021 - Taylor & Francis
The gastrointestinal (GI) system contains many different types of immune cells, making it a
key immune organ system in the human body. In the last decade, our knowledge has …
key immune organ system in the human body. In the last decade, our knowledge has …
Butyrate drives metabolic rewiring and epigenetic reprogramming in human colon cancer cells
L Wang, AAF Shannar, R Wu, P Chou… - Molecular nutrition & …, 2022 - Wiley Online Library
Scope Butyrate (B) is a short‐chain fatty acid produced by dietary fiber, known to inhibit
histone deacetylases (HDACs) and possess cancer‐preventive/anticancer effects. However …
histone deacetylases (HDACs) and possess cancer‐preventive/anticancer effects. However …
Gut microbiota influence anastomotic healing in colorectal cancer surgery through modulation of mucosal proinflammatory cytokines
Objective Colorectal cancer (CRC) is the third most diagnosed cancer, and requires surgical
resection and reconnection, or anastomosis, of the remaining bowel to re-establish intestinal …
resection and reconnection, or anastomosis, of the remaining bowel to re-establish intestinal …
Organoid technologies for the study of intestinal microbiota–host interactions
V Bozzetti, S Senger - Trends in molecular medicine, 2022 - cell.com
Postbiotics have recently emerged as critical effectors of the activity of probiotics and,
because of their safety profile, they are considered potential therapeutics for the treatment of …
because of their safety profile, they are considered potential therapeutics for the treatment of …
Biochemical and metabolical pathways associated with microbiota-derived butyrate in colorectal cancer and omega-3 fatty acids implications: A narrative review
AS Gheorghe, ȘM Negru, M Preda, RI Mihăilă… - Nutrients, 2022 - mdpi.com
Knowledge regarding the influence of the microbial community in cancer promotion or
protection has expanded even more through the study of bacterial metabolic products and …
protection has expanded even more through the study of bacterial metabolic products and …
Potential mechanisms of multimodal prehabilitation effects on surgical complications: a narrative review
Continuous advances in prehabilitation research over the past several decades have
clarified its role in improving preoperative risk factors, yet the evidence demonstrating …
clarified its role in improving preoperative risk factors, yet the evidence demonstrating …
Colorectal cancer: from risk factors to oncogenesis
VA Ionescu, G Gheorghe, N Bacalbasa, AL Chiotoroiu… - Medicina, 2023 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality worldwide.
Numerous pathophysiological mechanisms, such as abnormal cell proliferation, cell …
Numerous pathophysiological mechanisms, such as abnormal cell proliferation, cell …
Gut-microbiota derived bioactive metabolites and their functions in host physiology
Every individual harbours a complex, diverse and mutualistic microbial flora in their intestine
and over the time it became an integral part of the body, affecting a plethora of activities of …
and over the time it became an integral part of the body, affecting a plethora of activities of …
[PDF][PDF] Microbiota-derived metabolites in colorectal cancer patients in preoperative period.
K Kaźmierczak-Siedlecka… - European Review for …, 2023 - ppm.gumed.edu.pl
OBJECTIVE: Short-chain fatty acids (SCFAs) are microbial derived metabolites, which have
multiple beneficial properties. The amount of SCFAs depends on several factors, such as …
multiple beneficial properties. The amount of SCFAs depends on several factors, such as …