Immune reconstitution after allogeneic transplantation and expanding options for immunomodulation: an update

R Seggewiss, H Einsele - Blood, The Journal of the American …, 2010 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (HSCT) has advanced to a common
procedure for treating also older patients with malignancies and immunodeficiency …

[HTML][HTML] Improving engraftment and immune reconstitution in umbilical cord blood transplantation

R Danby, V Rocha - Frontiers in immunology, 2014 - frontiersin.org
Umbilical cord blood (UCB) is an important source of hematopoietic stem cells (HSC) for
allogeneic transplantation when HLA-matched sibling and unrelated donors (MUD) are …

Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation

R Admiraal, CCH de Koning, CA Lindemans… - Journal of Allergy and …, 2017 - Elsevier
Background Viral reactivations (VRs) after hematopoietic cell transplantation (HCT)
contribute to significant morbidity and mortality. Timely immune reconstitution (IR) is …

Immune restoration following hematopoietic stem cell transplantation: an evolving target

JJ Auletta, HM Lazarus - Bone marrow transplantation, 2005 - nature.com
Hematopoietic stem cell transplantation (HSCT) is the definitive cure for many malignant and
nonmalignant diseases. However, delays in immune reconstitution (IR) following HSCT …

Efficacy of a 3-day, low-dose treatment with 5-azacytidine followed by donor lymphocyte infusions in older patients with acute myeloid leukemia or chronic …

M Lübbert, H Bertz, R Wäsch, R Marks… - Bone marrow …, 2010 - nature.com
We have piloted a low-dose schedule of 5-azacytidine followed by donor lymphocyte
infusions (DLIs) in patients with relapse of AML or chronic myelomonocytic leukemia …

Treatment of relapsed acute myeloid leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a …

SJ Choi, JH Lee, S Kim, M Seol, YS Lee, JS Lee… - Leukemia, 2004 - nature.com
For patients with acute myeloid leukemia (AML) relapsed after allogeneic bone marrow
transplantation (BMT), donor leukocyte infusion (DLI) as sole therapy has very limited …

CD4+CD25+ Regulatory T Cell Depletion Improves the Graft-Versus-Tumor Effect of Donor Lymphocytes After Allogeneic Hematopoietic Stem Cell Transplantation

S Maury, FM Lemoine, Y Hicheri… - Science translational …, 2010 - science.org
Donor T cells play a pivotal role in the graft-versus-tumor effect after allogeneic
hematopoietic stem cell transplantation. Regulatory T cells (Tregs) may reduce alloreactivity …

Immune reconstitution and strategies for rebuilding the immune system after haploidentical stem cell transplantation

L Oevermann, P Lang, T Feuchtinger… - Annals of the New …, 2012 - Wiley Online Library
Haploidentical hematopoietic stem cell transplantation is a curative alternative option for
patients without an otherwise suitable stem cell donor. In order to prevent graft‐versus‐host …

Donor leukocyte infusion after hematopoietic stem cell transplantation in patients with juvenile myelomonocytic leukemia

A Yoshimi, P Bader, S Matthes-Martin, J Starý… - Leukemia, 2005 - nature.com
Juvenile myelomonocytic leukemia (JMML) is a clonal myeloproliferative disorder of early
childhood. In all, 21 patients with JMML who received donor leukocyte infusion (DLI) after …

Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte …

SJ Choi, JH Lee, S Kim, YS Lee, M Seol… - Bone marrow …, 2005 - nature.com
Donor leukocyte infusion (DLI) alone has very limited efficacy for patients with acute
lymphoblastic leukemia (ALL) who have relapsed after allogeneic bone marrow …