The role of platelets in immune-mediated inflammatory diseases

M Scherlinger, C Richez, GC Tsokos… - Nature Reviews …, 2023 - nature.com
Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …

Pneumonia-induced inflammation, resolution and cardiovascular disease: causes, consequences and clinical opportunities

C Stotts, VF Corrales-Medina, KJ Rayner - Circulation research, 2023 - Am Heart Assoc
Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

Isoliquiritigenin ameliorates ischemia-induced myocardial injury via modulating the Nrf2/HO-1 pathway in mice

D Yao, B Shi, S Wang, L Bao, M Tan… - Drug Design …, 2023 - Taylor & Francis
Background Oxidative stress and inflammatory reaction play critical roles in acute
myocardial infarction (AMI). Isoliquiritigenin (ISL), a flavonoid monomer extracted from …

Oxidative stress markers and antioxidant enzymes in children and adolescents with depressive disorder and impact of omega-3 fatty acids in randomised clinical trial

B Katrenčíková, M Vaváková, Z Paduchová, Z Nagyová… - Antioxidants, 2021 - mdpi.com
Oxidative stress (OS) is thought to play a role in mental disorders. However, it is not clear
whether the OS is the cause or consequence of the disorder. We investigated markers of …

M1 Bone Marrow‐Derived Macrophage‐Derived Extracellular Vesicles Inhibit Angiogenesis and Myocardial Regeneration Following Myocardial Infarction via the …

B Chen, L Luo, X Wei, D Gong, Z Li, S Li… - Oxidative Medicine …, 2021 - Wiley Online Library
Myocardial infarction (MI) is a severe cardiovascular disease. Some M1 macrophage‐
derived extracellular vesicles (EVs) are involved in the inhibition of angiogenesis and …

Therapeutic mechanisms of ginseng in coronary heart disease

MM Tang, ST Zhao, RQ Li, W Hou - Frontiers in Pharmacology, 2023 - frontiersin.org
Coronary heart disease (CHD) is the most common clinical manifestation of cardiovascular
disease. It is characterized by myocardial ischemia, which is caused by coronary …

[HTML][HTML] A Systematic Review on Advances in Management of Oxidative Stress-Associated Cardiovascular Diseases

S Jin, PM Kang - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such
as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension …

Lycopene alleviates oxidative stress-induced cell injury in human vascular endothelial cells by encouraging the SIRT1/Nrf2/HO-1 pathway

W Guo, D Huang, S Li - Clinical and Experimental Hypertension, 2023 - Taylor & Francis
Background and objective: Epidemiological research have displayed that dietary intake rich
in lycopene, an antioxidant, is negatively correlated with the risk of cardiovascular disease …

Can platelet activation result in increased plasma Aβ levels and contribute to the pathogenesis of Alzheimer's disease?

MG Carbone, G Pagni, C Tagliarini, BP Imbimbo… - Ageing Research …, 2021 - Elsevier
One of the central lesions in the brain of subjects with Alzheimer's disease (AD) is
represented by aggregates of β-amyloid (Aβ), a peptide of 40–42 amino acids derived from …

Gas plasma-induced platelet activation corresponds to reactive species profiles and lipid oxidation

J Striesow, J Wesche, N McKitterick, LM Busch… - Free Radical Biology …, 2023 - Elsevier
Surgical-induced hemostasis is a critical step in the closure of incisions, which is frequently
achieved via electrocauterization and subsequent tissue necrotization. The latter is …