Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

Abstract Machine learning is shaping up our lives in many ways. In analytical sciences,
machine learning provides an unprecedented opportunity to extract information from …

Early cancer detection has significant clinical value, but there remains no single method that
can comprehensively identify multiple types of early-stage cancer. Here, we report the …

The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …

Lung cancer has a high mortality rate, but an early diagnosis can contribute to a favorable
prognosis. A liquid biopsy that captures and detects tumor-related biomarkers in body fluids …

The discovery of the enhancement of Raman scattering by molecules adsorbed on
nanostructured metal surfaces is a landmark in the history of spectroscopic and analytical …

Tumor exosomes are promising biomarkers for early cancer diagnosis in a noninvasive
manner. However, precise capture and direct analysis of tumor-specific exosomes in …

Emerging evidence indicates that exosomes derived from gastric cancer cells enhance
tumor migration and invasion through the modulation of the tumor microenvironment …

As nanoscale extracellular vesicles, exosomes are secreted by various cell types, and they
are widely distributed in multiple biological fluids. Studies have shown that tumor-derived …

Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …